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21:11 EST 18th January 2020 | BioPortfolio

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Showing "Vaxigrip tetra Fluzone high dose Aldara Topical Cream" PubMed Articles 1–25 of 35,000+

Local dermal application of a compound lidocaine cream in pain management of cancer wounds.

The aim of this study was to explore the analgesic effect of local application of compound lidocaine/prilocaine cream on cancer wounds during wound care in order to reduce the amount of morphine intake or completely replace the systemic morphine administration and optimize the protocol for cancer wound pain management. All patients were enrolled with a visual analog scale (VAS) pain score ≥4. Before wound care, 60 patients were randomly divided into 2 groups of 30 each: morphine group (10 mg tablet); topi...


Compounded Topical Gabapentin for Neuropathic Pain: Does Choice of Base Affect Efficacy?

The objective of this study was to investigate the effect of Lipoderm Cream, VersaBase Gel, and Emollient Cream on the release and permeation of gabapentin formulated for neuropathic pain. Gabapentin of different strengths (1%, 5%, and 10%) was compounded with the bases, diffusion of the drug from thebases, and permeation through artificial skin model studied with Franz diffusionsystem. Steady-state flux, cumulative permeation, and lag times were calculated,and release mechanisms modelled with first order, ...

Treatment of Cabozantinib-Related Palmar-Plantar Erythrodysesthesia With Topical Sildenafil, Diclofenac, and Gabapentin Cream: A Case Report.


Guinea pig seborrheic dermatitis model of Malassezia restricta and the utility of luliconazole.

Seborrheic dermatitis (SD) is a multifactorial disease in which Malassezia restricta has been proposed as the predominant pathogenic factor. However, experimental evidence supporting this hypothesis is limited. A guinea pig SD model using a clinical isolate of M. restricta was used to elucidate the pathogenicity of M. restricta. Also, the efficacy of 1% luliconazole (LLCZ) cream, a topical imidazole derivative, against M. restricta was compared with that of a 2% ketoconazole (KCZ) cream in the same guinea p...

Efficacy of topical ivermectin and impact on quality of life in patients with papulopustular rosacea: A systematic review and meta-analysis.

Rosacea is a chronic inflammatory dermatosis involving certain facial areas. The multifactorial nature of this condition makes the management challenging. In addition, rosacea affects negatively to patients' quality of life (QoL). Despite the multiple articles supporting its use for papulopustular rosacea (PPR), there is a shortage of high-quality evidence researches comparing the efficacy of ivermectin cream (IVM) 1% with other available topical choices. Besides, the well-documented impaired of self-esteem...

Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium.

To evaluate the roles of known myopia-associated genetic variants for development of myopic macular degeneration (MMD) in individuals with high myopia (HM), using case-control studies from the Consortium of Refractive Error and Myopia (CREAM).

Speciation and isotopic characterization of mercury detected at high concentration in Pakistani hair samples.

Speciation and isotopic analyses of mercury (Hg) detected at high concentration (11-107 mg total Hg/kg) in the hair samples of Pakistani subjects were carried out to analyze whether the source of Hg was the skin cream or the soap they used. Liquid chromatography-ICP mass spectrometric speciation analysis revealed that the Hg in the hair was primarily inorganic. This result supported our assumption that skin care products were the source of the high concentration of Hg in hair, which was based on the stati...

Moderate influenza vaccine effectiveness against A(H1N1)pdm09 virus, and low effectiveness against A(H3N2) subtype, 2018/19 season in Italy.

: Influenza vaccines are updated every year to match the vaccine strains with currently circulating viruses; consequently influenza vaccine effectiveness (IVE) has to be assessed annually.: A test-negative case-control study was conducted within the context of the Italian sentinel influenza surveillance network to estimate IVE by age group, virus subtype, and vaccine brand in medically attended laboratory-confirmed influenza.: In Italy, the 2018/19 influenza season was characterized by the co-circulation of...

Dose- and starting time-dependent effect of the application of EGF to the regeneration of traumatic eardrum.

Some studies have shown that topical application of epidermal growth factor (EGF) accelerates healing in traumatic tympanic membrane perforations (TMPs), however, the optimal dose and starting time of application have not been established. To determine the optimal dose and starting time of application of EGF for the regeneration of TMPs. Patients with traumatic TMPs were first randomly assigned to low-dose EGF, high-dose EGF, and spontaneous healing groups. Then, the same patients were retrospectively ana...

Eradication of methicillin resistant S. aureus from human skin by the novel LL-37-derived peptide P10 in four pharmaceutical ointments.

Skin bacterial colonization/infections are frequent causes of morbidity in patients with chronic wounds and allergic/inflammatory skin diseases. This study aimed to develop a novel approach to eradicate methicillin-resistant Staphylococcus aureus (MRSA), further referred to as MRSA, from human skin. To achieve this, the stability and antibacterial activity of the novel LL-37-derived peptide P10 in four ointments was compared. Results indicate that P10 is chemically stable and antibacterial effective in hypr...

The Periodicity of Quadrilateral Tetra-Atomic Molecules.

We propose a periodic table for quadrilateral tetra-atomic molecules. Each molecule consists of four atoms and the geometric shapes of these molecules are studied by ab-initio calculations. It is found that by increasing the valence electron numbers, strong periodicity appears with many molecular properties. The periodic table for the quadrilateral tetra-atomic molecules is considered as an extension of Mendeleev's periodic table. It can also be used for estimating the unknown properties of tetra-atomic mol...

Clinical usefulness of dermoscopy in the management of lentigo maligna melanoma treated with topical imiquimod: a case report.

The importance of dermoscopy for diagnosing lentigo maligna melanoma (LMM) is well known. More recently, dermoscopy has been proposed as a useful tool also for the treatment choice and monitoring. Herein we present an 87 year-old woman, who was successfully treated with imiquimod 5% cream after post-surgical persistence of residual LMM and for whom dermoscopy was helpful to assist diagnosis, assess tumor persistence after surgery and its response to topical treatment with imiquimod. This article is protecte...

Response to the correspondence: a randomized, open, controlled trial of tretinoin 0.05% cream vs. low-dose oral isotretinoin for the treatment of field cancerization.

Long-term safety and efficacy of trifarotene 50μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne.

Treatment for both facial and truncal acne has not sufficiently been studied.

Copaiba oleoresin has topical antinociceptive activity in a UVB radiation-induced skin-burn model in mice.

Copaiba oleoresin, extracted from Copaifera L., is used as a wound healing, analgesic, antimicrobial and, mainly, anti-inflammatory agent. Thus, in this study we investigated the antinociceptive and anti-inflammatory effects of a topical formulation containing Copaiba oleoresin (3%) in a UVB radiation-induced skin burn model (0.75 J/cm) in mice and performed a cream-formulation stability study.

The high dose unfractionated heparin is related to less radial artery occlusion rates after diagnostic cardiac catheterisation: a single centre experience.

Transradial approach (TRA) has increasingly become the default strategy for cardiac catheterisation. However, TRA can result in several complications; radial artery occlusion (RAO) is the most unwilling complication. Unfractionated heparin (UFH) is an effective therapy in preventing RAO. The goal of this study was to evaluate whether weight-adjusted high dose UFH reduces the rate of RAO after diagnostic cardiac catheterisation compared to weight-adjusted standard dose UFH. A total of 1215 patients screened ...

Topical methotrexate 1% gel for treatment of vitiligo: A case report and review of the literature.

Vitiligo is quite a common hypopigmentary disorder, which may affect both children and adults with important psychological effects due to the well-known leopard skin-like appearance. Even if asymptomatic and not life threatening, vitiligo has to be increasingly studied and treated. Hitherto, the efficacy of topical methotrexate in treatment of vitiligo has not been reported. We herein reporting our preliminary observation on the promising efficacy of topical methotrexate in 1 patient with stable vitiligo. T...

On the use of the absorbed depth-dose measurements in the beam calibration of a surface electronic high-dose-rate brachytherapy unit, a Monte Carlo-based study.

To evaluate the use of the absorbed depth-dose as a surrogate of the half-value layer in the calibration of a high-dose-rate electronic brachytherapy (eBT) equipment. The effect of the manufacturing tolerances and the absorbed depth-dose measurement uncertainties in the calibration process are also addressed.

Observation of topical tacrolimus on high-risk penetrating keratoplasty patients: a randomized clinical trial study.

To evaluate the clinical efficacy of topical tacrolimus 0.1% and cyclosporine 1% on high-risk penetrating keratoplasty (PKP) patients.

Irritant contact dermatitis caused by a shower cream used as a leave-on product.

Irritant contact dermatitis can be caused by exposure to numerous irritants such as water, alkalis, acids, oils and organic solvents (1). Here, we present a patient who developed severe irritant contact dermatitis after using a shower cream as a moisturizing cream. The patient has provided written consent to publication of this case report. This article is protected by copyright. All rights reserved.

Exocyclically metallated tetrapyridinoporphyrazine as a potential photosensitizer for photodynamic therapy.

We report the first exocyclically metallated tetrapyridinoporphyrazine, [tetrakis-(trans-Pt(NH3)2Cl)-tetra(3,4-pyrido)porphyrazine-zinc(ii)](NO3)4 (4), synthesized in a multistep synthesis starting from 3,4-pyridinedicarbonitrile (1). The synthetic procedure involved a platination reaction of the intermediate tetra(3,4-pyrido)porphyrazine-zinc(ii) (2), whereby the zinc(ii) enhanced the solubility of the intermediate enabling the platination reaction. A similar approach to synthesize [tetrakis-(trans-Pt(NH3)...

Pilot study: Autologous platelet-rich plasma used in a topical cream for facial rejuvenation.

Platelet rich plasma (PRP) is traditionally used as an injectable material for enhanced healing, hair growth, and facial rejuvenation.

Individualised dosing algorithm and personalised treatment of high-dose rifampicin for tuberculosis.

To propose new exposure targets for Bayesian dose-optimisation suited for high-dose rifampicin and to apply them using measured plasma concentrations coupled with a Bayesian forecasting algorithm allowing predictions of future doses, considering rifampicin's auto-induction, saturable pharmacokinetics and high inter-occasion variability.

The effects of the addition of starter cultures and stevioside on technological low-fat fermented sherbet ice-cream without sugar.

The maintenance and strengthening of public health and the prevention of diseases associated with the malnutrition of children and adults is an urgent and acute problem facing the population of the whole world. Diabetes type 2 has become a serious problem for modern medicine. This disease is widespread throughout the world among children and adolescents. There are substantial grounds to believe that this global incidence is related to obesity and physical inactivity. There is a diverse assortment of ice-cre...

Diffuse Exfoliative Rash with Sepsis and Eosinophilia: A Case of Erythroderma?

BACKGROUND Erythroderma is an exfoliative dermatitis that manifests as generalized erythema and scaling that involves 90% of the body surface. If untreated, erythroderma can be fatal because of its metabolic burden and risk of secondary infections. CASE REPORT The patient was a 56-year-old male with prior rash attributed to group A Streptococcal cellulitis and discharged on Augmentin, Clindamycin with hydrocortisone cream, and Bactrim, but he had been noncompliant. He was admitted again for rash involving t...


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