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PubMed Journals Articles About "Volumetric Flow TIPS Portal Hypertension" RSS

21:46 EST 17th January 2020 | BioPortfolio

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Showing "Volumetric Flow TIPS Portal Hypertension" PubMed Articles 1–25 of 6,700+

Predicting Heart Failure After TIPS: Still More Questions Than Answers.

The transjugular intrahepatic portosystemic shunt (TIPS) is a percutaneous imaging-guided procedure that effectively reduces portal pressure by diverting blood from the portal to the systemic circulation. Despite being a very effective treatment for portal hypertension-related complications, the use of TIPS was hampered for many years by the high rate of TIPS dysfunction, an issue that has become almost anecdotal since the introduction of covered stents. (1)(1) Currently, development of post-TIPS hepatic en...


Long-term Outcome of Transjugular Intrahepatic Portosystemic Shunt in children with Portal Hypertension.

A proportion of children with chronic liver disease have severe portal hypertension (PH) and a preserved synthetic and biliary function. In our institution these children have been managed with Transjugular Intrahepatic Porto-systemic Shunts (TIPS). We aimed to evaluate the long-term patency of TIPS placed in paediatric patients with PH.

Letter to the Editor: Abdominal Surgery in Idiopathic Noncirrhotic Portal Hypertension: Is Preemptive TIPS Reducing Postoperative Complications?

We read with great interest the article by Elkrief et al. reporting long-term outcomes of abdominal surgery in patients with idiopathic noncirrhotic portal hypertension (INCPH) In a subgroup analysis, the authors compared the outcome of patients who had (n = 33) or did not have (n = 10) a preemptive transjugular intrahepatic portosystemic shunt (TIPS), showing that TIPS before surgery had no significant impact on postoperative outcomes. This retrospective subgroup analysis had some limitations. The comparis...


Role of Transjugular Intrahepatic Portosystemic Shunt in the Management of Portal Hypertension: Review and Update of the Literature.

Transjugular intrahepatic portosystemic shunt (TIPS) is a well-established procedure used in the management of complications of portal hypertension. Although the most robust evidence supports the use of TIPS as salvage therapy in variceal hemorrhage, secondary prophylaxis of variceal bleeding, and treatment of refractory ascites, there is also data to suggest its efficacy in other indications such as hepatic hydrothorax, hepatorenal syndrome, and Budd-Chiari syndrome. Recent literature also suggests that TI...

von Willebrand factor as a biomarker of clinically significant portal hypertension and severe portal hypertension: a systematic review and meta-analysis.

This meta-analysis was performed to investigate the correlation between von Willebrand factor (vWF) antigen and hepatic venous pressure gradient (HVPG) and to evaluate the diagnostic performance of vWF to detect clinically significant portal hypertension (CSPH) and severe portal hypertension (SPH).

Low-free triiodothyronine is associated with poor prognosis of portal hypertension in cirrhosis.

The role of thyroid function in the portal hypertension development and prognosis remains unclear. This study aimed to investigate the correlation between serum-free triiodothyronine (fT3) levels and the outcomes of cirrhotic portal hypertension.

Pharmacologic Management of Portal Hypertension.

Terlipressin, somatostatin, or octreotide are recommended as pharmacologic treatment of acute variceal hemorrhage. Nonselective β-blockers decrease the risk of variceal hemorrhage and hepatic decompensation, particularly in those 30% to 40% of patients with good hemodynamic response. Carvedilol, statins, and anticoagulants are promising agents in the management of portal hypertension. Recent advances in the pharmacologic treatment of portal hypertension have mainly focused on modifying an increased intrahe...

Portal Hypertension: Pathogenesis and Diagnosis.

Portal hypertension (PH) is an increase in the pressure gradient between portal vein and inferior vena cava. Increased resistance occurs at different levels within the portal venous system, followed by increased portal venous inflow. PH is the main driver of cirrhosis decompensation. Varices on endoscopy or portosystemic collaterals on imaging indicate PH. Although its cause is determined mostly via noninvasive tests, the gold standard to measure portal pressure in cirrhosis and determine its severity is he...

Esophageal Capsule Endoscopy (ECE) in Children and Young Adults with Portal Hypertension.

Variceal hemorrhage (VH) is a serious complication of portal hypertension (PH). We evaluated the feasibility, safety, and clinical impact of esophageal capsule endoscopy (ECE) in pediatric and young adult patients with known or suspected portal hypertension.

Peptide-based therapy in portal hypertension.

To summarize the use of gastrointestinal peptides in the management of portal hypertension.

Noncirrhotic Portal Hypertension: Current and Emerging Perspectives.

Idiopathic portal hypertension (IPH) and extrahepatic portal venous obstruction (EHPVO) are prototype noncirrhotic causes of portal hypertension (PHT), characterized by normal hepatic venous pressure gradient, variceal bleeds, and moderate to massive splenomegaly with preserved liver synthetic functions. Infections, toxins, and immunologic, prothrombotic and genetic disorders are possible causes in IPH, whereas prothrombotic and local factors around the portal vein lead to EHPVO. Growth failure, portal bili...

Portal Pressure in Non-Cirrhotic Portal Hypertension: To Measure or Not to Measure.

Non-cirrhotic portal hypertension (NCPH) is a heterogenous group of liver disorders characterized by elevated portal pressures in the absence of cirrhosis. Nodular regenerative hyperplasia (NRH) is a common cause of NCPH and can be due to drugs, hematological, autoimmune, and neoplastic disorders.(1) Patients with NCPH appear clinically distinct from cirrhotic patients due to their age, lack of significant alcohol intake or metabolic syndrome, and often carry associated risk factors (i.e. primary immunodefi...

Comparison of 4D Flow MRI to 2D Flow MRI in the pulmonary arteries in healthy volunteers and patients with pulmonary hypertension.

4D and 2D phase-contrast MRI (2D Flow MRI, 4D Flow MRI, respectively) are increasingly being used to noninvasively assess pulmonary hypertension (PH). The goals of this study were i) to evaluate whether established quantitative parameters in 2D Flow MRI associated with pulmonary hypertension can be assessed using 4D Flow MRI; ii) to compare results from 4D Flow MRI on a digital broadband 3T MR system with data from clinically established MRI-techniques as well as conservation of mass analysis and phantom co...

Surgical tips in extensive thrombectomy in living donor liver transplantation.

We appreciate the letter from Inonu group regarding our recent manuscript (1) regarding extensive thrombectomy in living donor liver transplantation (LDLT) with advanced portal vein thrombosis (PVT) (1). There are tips to complete safe ultrasound-guidance to treat advanced PVT. At the stump of the thrombosed portal vein (PV), the dissection plane should be not just on the original portal vein but keeping a thin layer of thrombus inside.

Non-invasive assessment of portal hypertension by multi-parametric magnetic resonance imaging of the spleen: A proof of concept study.

Non-invasive assessment of portal hypertension is an area of unmet need. This proof of concept study aimed to evaluate the diagnostic accuracy of a multi-parametric magnetic resonance technique in the assessment of portal hypertension. Comparison to other non-invasive technologies was a secondary aim.

Vascular Targets for the Treatment of Portal Hypertension.

Portal hypertension is the main driver for severe complications in patients with liver cirrhosis. With improved understanding of molecular pathways that promote hepatic vascular remodeling, vasoconstriction, and sinusoidal capillarization potential vascular targets for the treatment of portal hypertension have been identified. Inhibition of vascular endothelial and platelet-derived growth factors-driven angiogenesis has been shown to reduce portal pressure and decrease hepatic inflammation. Angiopoietin/Tie...

Application study of ultrasound-guided percutaneous portal vein punctures combined with bi-directionalangiography in the treatment by TIPS.

To investigate the safety, feasibility, and preliminary clinical experience of ultrasonic guided percutaneous portal vein punctures combined bi-directional angiography in the treatment by transjugular intrahepatic portosystemic shunt(TIPS). From January 2016 to June 2018, 15 patients with TIPS from our hospital who were treated by ultrasonic guided percutaneous portal vein punctures combined with bi-directional angiography were enrolled,and were recruited as experimental group. During the same period, 30 p...

Portal hypertension evolving from sickled hepatopathy: Could hepatic venous Doppler ultrasound be beneficial in its evaluation?

Sickle cell intrahepatic cholestasis involves sickling within hepatic sinusoids leading to vascular stasis and localized hypoxia resulting in ballooning of the hepatocytes causing a direct back pressure effect with resultant intracanalicular cholestasis. Vascular stasis may ultimately lead to portal hypertension. We proposed to document findings suggestive of portal hypertension evolving from hepatopathy in steady-state sickle cell disease (SCD) patients using hepatic venous Doppler ultrasound.

Intrahepatic arterial localizer guided transjugular intrahepatic portosystemic shunt placement: Feasibility, efficacy, and technical success assessed by a case series-a STROBE- compliant article.

Transjugular intra-hepatic portosystemic shunts (TIPS) had been considered a standard procedure in patients suffering from portal hypertension. The most challenging step in TIPS placement is blind puncture of the portal vein. We had established a localization method by introducing an Intra-Hepatic Arterial based puncture directing Localizer (IHAL) with the assistance of the enhanced computed tomography (CT) reconstruction. This study aimed to evaluate the feasibility, efficacy, and technical success of this...

Clinical Characteristics and Risk Factors for Sinistral Portal Hypertension Associated with Moderate and Severe Acute Pancreatitis: A Seven-Year Single-Center Retrospective Study.

BACKGROUND This study aimed to assess the prevalence, clinical characteristics, and risk factors for sinistral portal hypertension in patients with moderate or severe acute pancreatitis. MATERIAL AND METHODS A retrospective study included 825 patients with moderate or severe acute pancreatitis. Clinical and demographic data, the Acute Physiology and Chronic Health Evaluation (APACHE II) and the Ranson scores for severity of acute pancreatitis, and the computed tomography (CT) severity index (CTSI) were eval...

Left-sided Portal Hypertension After Pancreaticoduodenectomy With Resection of the Portal Vein/Superior Mesenteric Vein Confluence in Patients With Pancreatic Cancer: A Project Study by the Japanese Society of Hepato-Biliary-Pancreatic Surgery.

The aim of this study was to evaluate how often left-sided portal hypertension (LPH) develops and how LPH affects the long-term outcomes of patients with pancreatic cancer treated with pancreaticoduodenectomy (PD) and resection of the portal vein (PV)/superior mesenteric vein (SMV) confluence.

Portal hyperperfusion after major liver resection and associated sinusoidal damage is a therapeutic target to protect the remnant liver.

Extended liver resection results in the loss of a large fraction of the hepatic vascular bed and thereby abrupt alterations in the perfusion of the remnant liver. Mechanisms of hemodynamic adaptation and associated changes in oxygen metabolism after liver resection and the effect of mechanical portal blood flow reduction were assessed. A pig model (n=16) of extended partial hepatectomy that included continuous observation for 24 hours under general anesthesia was established. Pigs were randomly separated in...

Prophylactic Transjugular Intrahepatic Portosystemic Shunt Placement for Cirrhosis Management in Pregnancy.

Although pregnancy is uncommon in patients with cirrhosis, worsening portal hypertension increases the risk of variceal hemorrhage and bleeding during Cesarean section [1-3]. Bleeding typically occurs in the third trimester, when maternal blood volume maximally expands and the fetus increases intra-abdominal pressure. Endoscopic therapy is first-line therapy [1], but transjugular intrahepatic portosystemic shunt (TIPS) procedure, may be required as salvage therapy [1]. Here we present the use of prophylacti...

Pulmonary Complications of Portal Hypertension.

The most common pulmonary complications of chronic liver disease are hepatic hydrothorax, hepatopulmonary syndrome, and portopulmonary hypertension. Hepatic hydrothorax is a transudative pleural effusion in a patient with cirrhosis and no evidence of underlying cardiopulmonary disease. Hepatic hydrothorax develops owing to the movement of ascitic fluid into the pleural space. Hepatopulmonary syndrome and portopulmonary hypertension are pathologically linked by the presence of portal hypertension; however, t...

An Update: Portal Hypertensive Gastropathy and Colopathy.

Complications of portal hypertension include portal hypertensive gastropathy and colopathy. These disorders may cause chronic or acute gastrointestinal bleeding. The diagnosis is made endoscopically; therefore, there is great variability in their assessment. Portal hypertensive gastropathy can range from a mosaic-like pattern resembling snakeskin mucosa to frankly bleeding petechial lesions. Portal hypertensive colopathy has been less well-described and is variably characterized (erythema, vascular lesions,...


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