PubMed Journals Articles About "Intervention Inflammation" RSS

16:09 EDT 17th October 2018 | BioPortfolio

Intervention Inflammation PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Intervention Inflammation articles that have been published worldwide.

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Showing "intervention Inflammation" PubMed Articles 1–25 of 8,100+

Uroseptic Shock Can Be Reversed by Early Intervention Based on Leukocyte Count 2 h Post-operation: Animal Model and Multicenter Clinical Cohort Study.

This study investigated whether early intervention based on leukocyte count (WBC) of less than 2.85 × 10/L obtained within 2 h post-operatively may ameliorate the uroseptic shock induced by upper urinary tract endoscopic lithotripsy (UUTEL). Urosepsis was induced in 30 rabbits and assigned to three groups: Control-I, WBC-I, and Shock-I. Control-I: Non-intervention control.

Nordihydroguaiaretic acid can suppress progression of experimental autoimmune encephalomyelitis.

Multiple sclerosis (MS) is a poorly understood disease mechanistically. MOG35-55 peptide induced experimental autoimmune encephalomyelitis (EAE) is a broadly used model to study MS. Using this model we have earlier shown that the antioxidant tempol or the small molecule inhibitor of p38 SB203580 can effectively prevent EAE progression. This effect was mediated by means of regulating immune inflammation, signaling by the p38MAPK-SGK1 pathway, and oxidative stress. However, there is a need to test drugs that ...

Human Umbilical Cord Blood Therapy Protects Cerebral White Matter from Systemic LPS Exposure in Preterm Fetal Sheep.

Infants born preterm following exposure to in utero inflammation/chorioamnionitis are at high risk of brain injury and life-long neurological deficits. In this study, we assessed the efficacy of early intervention umbilical cord blood (UCB) cell therapy in a large animal model of preterm brain inflammation and injury. We hypothesised that UCB treatment would be neuroprotective for the preterm brain following subclinical fetal inflammation.

Exploring the role of gratitude and support-giving on inflammatory outcomes.

Although there has been much interest in understanding the effect of gratitude on health-related outcomes, this remains an understudied area of research, particularly regarding mechanisms and measurement of biological outcomes. The present study explored whether a gratitude intervention could reduce inflammatory outcomes and whether this occurred through increased support-giving. Healthy women ( = 76) were randomly assigned to a 6-week gratitude intervention (i.e., writing on topics intended to induce grati...

Inflammation, Superadded Inflammation, and Out-of-Proportion Inflammation in Atherosclerosis.

Inflammation arising from obesity reduces taste bud abundance and inhibits renewal.

Despite evidence that the ability to taste is weakened by obesity and can be rescued with weight loss intervention, few studies have investigated the molecular effects of obesity on the taste system. Taste bud cells undergo continual turnover even in adulthood, exhibiting an average life span of only a few weeks, tightly controlled by a balance of proliferation and cell death. Recent data reveal that an acute inflammation event can alter this balance. We demonstrate that chronic low-grade inflammation broug...

Evolution in the Surgical Management of Chronic Rhinosinusitis: Current Indications and Pitfalls.

Chronic rhinosinusitis (CRS) consists of a range of inflammatory conditions in the sinuses that may result in clinical symptoms and the underlying pathophysiology and its relationship to lower airway disease is complex. Current definitions of CRS may serve more as an indication for potential surgical intervention rather than a marker of disease state. CRS can be asymptomatic and may require medical management to avoid disease progression and to minimize the risk of lower airway disease. Endoscopic surgery h...

Comparative efficacy of a 12 week yoga-based lifestyle intervention and dietary intervention on adipokines, inflammation, and oxidative stress in adults with metabolic syndrome: a randomized controlled trial.

The present randomized controlled trial (RCT) evaluated the comparative efficacy of 12 week yoga-based lifestyle intervention (YBLI) and dietary intervention (DI) alone on adipokines, inflammation, and oxidative stress in Indian adults with metabolic syndrome (Met S). A parallel, two arm, RCT was conducted in Integral Health Clinic (IHC), All India Institute of Medical Sciences, India from 2012 to 2014. IHC is an outpatient facility conducting YBLI programs for prevention and management of chronic diseases....

Curcumin confers hepatoprotection against AFB-induced toxicity via activating autophagy and ameliorating inflammation involving Nrf2/HO-1 signaling pathway.

The current study demonstrated curcumin intervention against AFB-indeuced hepatotoxicity. The hallmarks of autophagy and inflammation were assessed by transmission electron microscopy, RT-PCR and western blot. Besides, normal cellular morphology, autophagosomes were found in control and curcumin control group. In contrast, fragmented and swollen mitochondria, irregular shaped nuclei and fat droplets were visible but autophagosomes disappear in AFB-treated group. The mRNA and protein expression levels of aut...

The functional effect of atorvastatin dose-dependent via inflammation factors on acute ST segment elevation myocardial infarction after emergency percutaneous coronary intervention.

To investigate the effect of different doses of atorvastatin on patients with acute ST segment elevation myocardial infarction (MI) after emergency percutaneous coronary intervention (PCI).

The airway inflammation induced by nasal inoculation of PM2.5 and the treatment of bacterial lysates in rats.

Particulate matter (PM) is one of the most important environmental issues in China. This study aimed to explore the correlation between PM2.5 and airway inflammation in healthy rats. The PM2.5 group was given an intranasal instillation of PM2.5 suspension on 15 consecutive days, and each received oral saline from day 16 to 90. The BV intervention group was treated as the PM2.5 exposure group, except that BV instead of saline was given daily. A histopathologic examination was performed to evaluate the airway...

Strengthening Youth Friendly Health Services through Expanding Method Choice to include Long-Acting Reversible Contraceptives for Ethiopian Youth.

Despite robust evidence regarding long-acting reversible contraceptive (LARC) low failure rates, immediate return to fertility and safety, LARC uptake among youth is low. We evaluated the effect on contraceptive uptake of training youth-friendly service providers to counsel and provide all contraceptive methods including LARCs in the same unit. A convenience purposive sampling technique was used to select 20 youth friendly health units; ten each in Amhara and Tigray regions, Ethiopia; randomly allocated to ...

Intervention planning for the REDUCE maintenance intervention: a digital intervention to reduce reulceration risk among patients with a history of diabetic foot ulcers.

To develop a comprehensive intervention plan for the REDUCE maintenance intervention to support people who have had diabetic foot ulcers (DFUs) to sustain behaviours that reduce reulceration risk.

Personalized Cardio-Metabolic Responses to an Anti-Inflammatory Nutrition Intervention in Obese Adolescents: A Randomized Controlled Crossover Trial.

Chronic inflammation and hypoadiponectinemia are characteristic of obesity-induced insulin resistance (IR). The effect of an anti-inflammatory nutrition supplement (AINS) on IR and adiponectin biology in overweight adolescents was investigated. The secondary objective was to examine the extent to which individuals' biomarker profiles, derived from baseline phenotypes, predicted response or not to the AINS. Additionally, the impact of DNA methylation on intervention efficacy was assessed.

Potential application of testosterone replacement therapy as treatment for obesity and type 2 diabetes in men.

Sedentary lifestyle and over-nutrition are the main causes of obesity and type 2 diabetes (T2D). However, the same causes are major triggers of hypogonadism. Many T2D patients show low testosterone levels while hypogonadal men seem to be prone to become diabetic. Testosterone plays a major role in the regulation of muscle mass, adipose tissue, inflammation and insulin sensitivity and is therefore indirectly regulating several metabolic pathways, while T2D is commonly triggered by insulin resistance, increas...

Molecular imaging of coronary inflammation.

Coronary inflammation is related to atherosclerotic disease and, less frequently, systemic vasculitis. Regardless of the etiology, coronary inflammation is associated with adverse cardiac events. Molecular imaging with F-fluorodeoxyglucose (FDG) positron emission tomography (PET/CT) allows in vivo assessment of coronary inflammation and evaluation of response to therapy. The aim of this review is to give an update on the recent development of FDG-PET/CT, discuss the potential roles of coronary inflammation ...

Intervention delivery fidelity assessment of a counseling-based intervention for promoting smoking reduction and increasing physical activity.

The aims of this study were to (1) develop an approach to assess the delivery fidelity of a complex intervention to simultaneously increase physical activity and reduce smoking and (2) use this approach to assess the variation of fidelity across the delivery of different intervention components of the intervention.

The efficacy of curcumin in managing acute inflammation pain on the post-surgical removal of impacted third molars patients: A randomized controlled trial.

Curcumin is a turmeric contained active ingredient that has been proven to be effective in treating pain and inflammation due to its analgesic as well as anti-inflammation potential. Odontectomy, on the other hand, has been well known for its post-procedure acute inflammation pain.

Early intervention for personality disorder.

Specialized treatments for personality disorder are usually offered late in the course of the disorder, to a small number of help-seeking individuals with entrenched disability. Intervention during the early stages of personality disorder might help to decrease the persistence and/or the severity of personality disorder and to prevent the cascading of secondary psychopathology and psychosocial disability. Research regarding the understanding of and appropriate treatment for early stage personality disorder ...

Genetic disposition to inflammation and response to antidepressants in major depressive disorder.

Inflammation may play an important role in depression and its treatment. A previous study found that increased C-reactive protein (CRP), a marker of systemic inflammation, is associated with worse response to the serotonergic antidepressant escitalopram and better response to the noradrenergic antidepressant nortriptyline. It is unclear whether this reflects genetic disposition to inflammation.

Influence of Inflammation on the Pharmacokinetics of Perampanel.

It is well-known that the pharmacokinetics of various drugs are influenced by inflammation. This study evaluated the relationship between C-reactive protein (CRP; an inflammation marker) and the pharmacokinetics of perampanel.

The PRISM Intervention for Adolescents and Young Adults With Cancer: Paying Attention to the Patient as a Whole Person.

The Promoting Resilience in Stress Management intervention brings welcome news to adolescents and young adults with cancer, with an increase in resilience, improved cancer-related quality of life, and decreased overall distress among patients who participated in the intervention in comparison with controls. As the investigators think about their next steps, consideration of how best to expand this intervention to underserved populations should be a priority.

HDAC4 regulates vascular inflammation via activation of autophagy.

Angiotensin II (Ang II) causes vascular inflammation, leading to vascular endothelial cell dysfunction, and is associated with the development of cardiovascular diseases. Therefore, interventions in inflammation may contribute to the reduction of cardiovascular diseases. Here, we aim to demonstrate that HDAC4, one of class IIa family histone deacetylases (HDACs) members, promotes autophagy-dependent vascular inflammation.

Resolution of inflammation in neuromyelitis optica spectrum disorders.

Neuromyelitis optica spectrum disorders (NMOSD) are a spectrum of neuroinflammatory disorders associated with autoimmune antibodies against aquaporin-4 (AQP4). Accumulating evidence suggests that inflammation is involved in NMOSD pathogenesis. Resolution of inflammation, which is a highly regulated process mediated by specialized pro-resolving lipid mediators (SPMs) is important to prevent over-responsive inflammation. Deficiency in resolution of inflammation may lead to or accelerates inflammatory diseases...

Acute and chronic effects of exercise on the kynurenine pathway in humans - A brief review and future perspectives.

Tryptophan (TRP) is an essential amino acid. Metabolites of TRP have been identified as important mediators in immune regulation and function of the central nervous system. Inflammation strongly stimulates to the breakdown of TRP into Kynurenine (KYN), representing the initial step of the KYN pathway. Recently, exercise interventions have been able to demonstrate a modification of the KYN pathway plausibly by altering inflammation. However, modifications differ between acute and chronic exercise interventio...

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