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Wyeth Study To Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants

2014-08-27 03:38:56 | BioPortfolio

Summary

The purpose of this study is to assess the safety,tolerability and immunogenicity of manufacturing scale 13-valent pneumococcal conjugate(13vPnC) vaccine compared to pilot scale 13vPnC in healthy infants when given with routine paediatric vaccines

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Conditions

Pneumococcal Vaccines

Intervention

13-valent Pneumococcal Conjugate Vaccine

Location

Torun
Bydgoszcz
Poland
87-100

Status

Completed

Source

Wyeth

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:38:56-0400

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Medical and Biotech [MESH] Definitions

A pneumococcal vaccine which 7 pneumococcal serotypes (6B, 14, 19F, 23F, 18C, 4, 9V), each conjugated individually to the outer membrane protein complex of NEISSERIA MENINGITIDIS.

Vaccines or candidate vaccines used to prevent infections with STREPTOCOCCUS PNEUMONIAE.

Vaccines or candidate vaccines containing antigenic polysaccharides from Haemophilus influenzae and designed to prevent infection. The vaccine can contain the polysaccharides alone or more frequently polysaccharides conjugated to carrier molecules. It is also seen as a combined vaccine with diphtheria-tetanus-pertussis vaccine.

Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.

A febrile disease caused by STREPTOCOCCUS PNEUMONIAE.

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