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A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults

2014-08-27 03:39:05 | BioPortfolio

Summary

Casopitant may affect liver enzymes that metabolize ketoconazole. This study is designed to test the safety and the extent of the Casopitant affect on ketoconazole levels in healthy human subjects.

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Healthy Subjects

Intervention

Casopitant, Ketoconazole

Location

GSK Investigational Site
Overland Park
Kansas
United States
66211

Status

Completed

Source

GlaxoSmithKline

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:39:05-0400

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Medical and Biotech [MESH] Definitions

Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)

Negative test results in subjects who possess the attribute for which the test is conducted. The labeling of diseased persons as healthy when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)

Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.

Books intended for use in the study of specific subjects, containing systematic presentation of the principles and essential knowledge of the subjects.

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