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Phase II Dose-Ranging Study of OrthoDerm Patch for Patients With Tennis Elbow

2014-08-27 03:39:37 | BioPortfolio

Summary

The purpose of the study is to evaluate the effectiveness and safety of the use of low-dose nitroglycerin transdermal patches to treat pain and function in chronic tennis elbow.

Description

Chronic tendonitis remains difficult to treat. Nitric oxide has been demonstrated to stimulate tenocytes to proliferate, differentiate and produce matrix components including collagen. Studies have demonstrated that nitroglycerin transdermal patches, which release nitric oxide, reduce pain and increase function in patients with chronic tendonitis. The purpose of the present study is to examine the efficacy of three dose levels of nitroglycerin, compared to placebo, in reducing pain and increasing function in patients with chronic (greater than three months' duration) lateral epicondylitis.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Tendonitis

Intervention

OrthoDerm transdermal nitroglycerin patch

Location

to Be Determined
Warsaw
Poland

Status

Not yet recruiting

Source

Cure Therapeutics

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:39:37-0400

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