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The purposes of this study are:
- to find the highest tolerable dose of HKI-272 in combination with Paclitaxel
- to assess the safety of the combination of the two drugs
- to obtain preliminary information on whether the combination of the two drugs has any effect on solid tumors
The study will be conducted in two parts. In the first part, testing will be done to determine the highest tolerable dose of HKI-272 and Paclitaxel in patients with advanced solid tumors.
Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Advanced Breast Cancer
Active, not recruiting
Published on BioPortfolio: 2014-08-27T03:39:44-0400
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An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
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