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Topical Tacrolimus 0.03% Ointment for Intractable Allergic Conjunctivitis: An Open Label Pilot Study

2014-07-23 21:30:02 | BioPortfolio

Summary

The purpose of this study is to determine the efficacy, tolerance and safety of tacrolimus 0.03% ointment in the treatment of intractable allergic conjunctivitis.

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Allergic Conjunctivitis

Intervention

Tacrolimus 0.03% ointment (Protopic)

Location

Assaf Harofeh Medical Center, Department of Ophthalmology
Zerifin
Israel
70300

Status

Active, not recruiting

Source

Assaf-Harofeh Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:30:02-0400

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PubMed Articles [794 Associated PubMed Articles listed on BioPortfolio]

Skin reactivity in allergic conjunctivitis.

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Medical and Biotech [MESH] Definitions

Conjunctivitis due to hypersensitivity to various allergens.

Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.

A long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. The drug is well tolerated and has no anticholinergic side effects.

A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.

An antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.

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Relevant Topic

Allergies
The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...


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