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Ph1 Lobeline Interaction Study - 1

2014-08-27 03:39:58 | BioPortfolio

Summary

The purpose of this study is to determine if there are significant cardiovascular or other interactions between sublingual lobeline and intravenous methamphetamine.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Methamphetamine Dependence

Intervention

Lobeline

Location

Langley Porter Psychiatric Institute
San Francisco
California
United States
94143

Status

Recruiting

Source

National Institute on Drug Abuse (NIDA)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:39:58-0400

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Medical and Biotech [MESH] Definitions

Strong dependence, both physiological and emotional, upon morphine.

Strong dependence, both physiological and emotional, upon heroin.

A plant genus of the family CAMPANULACEAE used medicinally and is a source of LOBELINE.

A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.

A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. It also has a depressant action on the cough center and may be given to control intractable cough associated with terminal lung cancer. Methadone is also used as part of the treatment of dependence on opioid drugs, although prolonged use of methadone itself may result in dependence. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)

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