Advertisement

Topics

Evaluation of the Safety and Efficacy of CosmetaLife™ for the Correction of Nasolabial Folds

2014-07-23 21:34:25 | BioPortfolio

Summary

This is a randomized, double-blind study to evaluate the safety and effectiveness of CosmetaLife injectable dermal filler for the correction of wrinkles and folds, such as nasolabial folds (i.e., smile lines).

Description

Patients with negative allergy test results will be randomized to receive CosmetaLife in one nasolabial fold and Control in the nasolabial fold on the opposite side of the face. Each subject will serve as his or her own control, allowing for comparison of the outcome between the contra-lateral sides. Patients will be followed at 2 weeks and 3, 6, 9 and 12 months post treatment for assessment of safety and effectiveness.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Facial Wrinkles

Intervention

Injectable dermal filler

Location

Beauty Renewed
Tracy
California
United States
95376

Status

Active, not recruiting

Source

Cosmeta

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:34:25-0400

Clinical Trials [500 Associated Clinical Trials listed on BioPortfolio]

Multicenter Study of the Safety and Effectiveness of Dermal Filler, Belotero®.

This is a study to find out how an investigational product, Belotero®, compares to a second product in people with facial wrinkles, such as nasolabial folds. Nasolabial folds are wrinkle...

Outcomes and Patient Experience After Soft Tissue Dermal Filler Injections

Purpose of the study: The overall goal of this study is to better understand patient experience with injectable facial fillers so that the investigators may provide the best results for t...

Evaluation of Radiesse® Injectable Dermal Filler for Hand Rejuvenation

The purpose of this study is to assess the safety and effectiveness of Radiesse® Injectable Dermal Filler for hand rejuvenation.

Evaluation of Pain With Lidocaine-Mixed Radiesse® Injectable Dermal Filler

To assess pain during nasolabial fold treatment using Radiesse® Injectable Dermal Filler mixed with lidocaine.

A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device (DGE) and an FDA Approved Device for the Correction of Nasolabial Folds (NLFs)

The purpose of this research study is to evaluate the safety and effectiveness of injection with DGE Injectable Gel (manufactured by Genzyme Biosurgery) as compared to injection with a Foo...

PubMed Articles [1645 Associated PubMed Articles listed on BioPortfolio]

Dermal Filler Presenting as Lobular Radiopacities in an Edentulous Patient: A Clinical Report.

This clinical report describes the unusual appearance of radiopacities, lobular in nature, observed on a dental panoramic image of an edentulous patient. Upon questioning, the patient described a hist...

Facial Volume Restoration with Permanent Dermal Filler (Artecoll-4) in Chinese Women.

Sectioned images and 3D models of a cadaver head with reference to dermal filler injection.

The purpose of this study was to describe anatomical consideration with reference to dermal filler injection on sectioned images and three dimensional (3D) models using Visible Korean for medical educ...

Intra-Arterial Thrombolytic Therapy Is Not a Therapeutic Option for Filler-Related Central Retinal Artery Occlusion.

Cosmetic facial filler-related central retinal artery occlusion (CRAO) is a devastating complication of facial hyaluronic acid (HA) injection and can be managed by intra-arterial thrombolytic therapy ...

Unusual Aspergillus Infection After Dermal Filler Injection.

According to a great desire for facial rejuvenation, dermal filler is promising for improving people's appearance without surgery. In a society of plastic surgery, injection of dermal filler is one of...

Medical and Biotech [MESH] Definitions

Severe or complete loss of facial muscle motor function. This condition may result from central or peripheral lesions. Damage to CNS motor pathways from the cerebral cortex to the facial nuclei in the pons leads to facial weakness that generally spares the forehead muscles. FACIAL NERVE DISEASES generally results in generalized hemifacial weakness. NEUROMUSCULAR JUNCTION DISEASES and MUSCULAR DISEASES may also cause facial paralysis or paresis.

Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.

The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear.

Neuralgic syndromes and other conditions which feature chronic or recurrent FACIAL PAIN as the primary manifestation of disease. Disorders of the trigeminal and facial nerves are frequently associated with these conditions.

Diseases of the facial nerve or nuclei. Pontine disorders may affect the facial nuclei or nerve fascicle. The nerve may be involved intracranially, along its course through the petrous portion of the temporal bone, or along its extracranial course. Clinical manifestations include facial muscle weakness, loss of taste from the anterior tongue, hyperacusis, and decreased lacrimation.

More From BioPortfolio on "Evaluation of the Safety and Efficacy of CosmetaLife™ for the Correction of Nasolabial Folds"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Allergies
The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...


Searches Linking to this Trial