Topics

Voice Prosthesis Made in Porous Titanium After Total Laryngectomy or Pharyngolaryngectomy

2014-07-23 21:34:57 | BioPortfolio

Summary

The benefits of this new material, as demonstrated in animal studies and preliminary studies in man, could provide the answer to problems encountered by surgeons in the field of phonatory implants. This novel application is a step towards resolving the very real problems which still exist in the field today. The functional concept, which will allow better control over integrating implants in tissue, should also, it is hoped, favour cellular colonization, thereby fulfilling a currently unmet medical need. The aim is to avoid well-identified potential complications linked to the use of silicone-only implants (with or without a surface coating), like leakage around the prosthesis (by cellular colonization), and so reduce the risk of protrusion/extrusion of the prosthesis as far as possible, and to avoid trauma to the peri-prosthetic tissues by repeated interventions

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Pharyngeal Neoplasms

Intervention

prothesis voice, total laryngectomy

Location

Service d'ORL et de Chirurgie Cervico-Faciale, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg
Strasbourg
France
67082

Status

Recruiting

Source

University Hospital, Strasbourg, France

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:34:57-0400

Clinical Trials [560 Associated Clinical Trials listed on BioPortfolio]

A Novel Modified Tracheo-Esophageal Voice Prosthesis for Total Laryngectomy Patients

This study is being conducted at Healthcare Global Enterprises Ltd to evaluate the role of a novel Tracheo-Esophageal voice Prosthesis for total laryngectomy +/- partial pharyngectomy pati...

Cost-effectiveness Analysis of Vocal Rehabilitation With Strengthened Tracheoesophageal Voice Implant Prosthesis Versus Standard Voice Prosthesis in Case of Repeated Intra-prosthetic Leakage After Total Laryngectomy

The purpose of this study is to determine the cost-effectiveness of vocal rehabilitation with reinforced inter-tracheoesophageal voice prosthesis versus standard voice prosthesis in case o...

Concurrent Chemoradiation Versus Surgery With Adjuvant Therapy in Advanced Laryngopharyngeal Cancers

Surgery with post operative radiotherapy (PORT) had been the mainstay of treatment for advanced laryngeal-pharyngeal cancers (ALHC) until the eighth decade of the past century. Total laryn...

Clinical Feasibility of New Tracheoesophageal Puncture Set

During a total laryngectomy a puncture is created in the tracheoesophageal wall and a voice prosthesis is inserted. With this voice prosthesis the patient learns to speak again. During thi...

Laryngectomy Education

Patients undergoing total laryngectomy are at high risk for 30-day unplanned readmission. Many of these readmissions are related to stomal care, and it is thought that the readmissions cou...

PubMed Articles [5822 Associated PubMed Articles listed on BioPortfolio]

Education, counseling, support groups, and provider knowledge of total laryngectomy: The patient's perspective.

Studies over a 40 year period have reported inadequate education and counseling for persons with laryngectomy; however, several long-term trends, including centralization of laryngectomy surgeries i...

Bilateral infrahyoid muscle, myofascial and myoperichondrial flaps in laryngectomy.

Protection of suture line of neopharynx after a laryngectomy or near total laryngectomy with vascularized tissues is of utmost importance in preventing a wound related complication.

Comparison of Voice Handicap Index in Patients with Esophageal and Tracheoesophageal Speech after Total Laryngectomy.

Successful speech rehabilitation has a great impact on the quality of life in totally laryngectomized patients.

Does Thyroid Gland Preserving Total Laryngectomy Affect Oncological Control in Laryngeal Carcinoma?

Thyroid lobectomy is recommended with total laryngectomy in the National Comprehensive Cancer Network guidelines. However, it is associated with a 32% to 89% risk of hypothyroidism, which is a problem...

Care of laryngectomy stomas in general practice.

Laryngectomy stomas are formed following excision of the larynx, usually for the treatment of an underlying malignancy. This is a permanent stoma in which the trachea is separated from the oesophagus...

Medical and Biotech [MESH] Definitions

Total or partial excision of the larynx.

Pathological processes that affect voice production, usually involving VOCAL CORDS and the LARYNGEAL MUCOSA. Voice disorders can be caused by organic (anatomical), or functional (emotional or psychological) factors leading to DYSPHONIA; APHONIA; and defects in VOICE QUALITY, loudness, and pitch.

That component of SPEECH which gives the primary distinction to a given speaker's VOICE when pitch and loudness are excluded. It involves both phonatory and resonatory characteristics. Some of the descriptions of voice quality are harshness, breathiness and nasality.

Tumors or cancer of the PHARYNX.

A variety of techniques used to help individuals utilize their voice for various purposes and with minimal use of muscle energy.

More From BioPortfolio on "Voice Prosthesis Made in Porous Titanium After Total Laryngectomy or Pharyngolaryngectomy"

Quick Search

Searches Linking to this Trial