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Diet, Obesity and Genes (DiOGenes)

2014-08-27 03:41:58 | BioPortfolio

Summary

Study Title: Diogenes, A randomised controlled trial comparing the effect of reduced-fat diets varying in glycaemic index (high vs. low) and protein content (high vs. normal) on bodyweight in overweight and obese subjects after an initial weight loss.

Description

DiOGenes is a randomised controlled dietary intervention study in obese/overweight families (adults and children) in 8 different European countries, testing the efficacy and safety of diets differing in Glycaemic Index (GI) and protein content.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Conditions

Obesity

Intervention

High or low Glycemic Index and high or low Protein Diet

Location

Arne V. Astrup
Copenhagen
Denmark

Status

Active, not recruiting

Source

University of Copenhagen

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:41:58-0400

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PubMed Articles [43987 Associated PubMed Articles listed on BioPortfolio]

Changes in Plasma Metabolite Concentrations after a Low-Glycemic Index Diet Intervention.

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Medical and Biotech [MESH] Definitions

A course of food intake prescribed for patients, that limits the amount of foods with a high GLYCEMIC INDEX.

A diet that consists mainly of foods with a high content of protein and limited amounts of CARBOHYDRATES.

A diet that includes foods with a high protein content.

A quantitative value of a measured amount of a specific food that is equal to the GLYCEMIC INDEX of that food multiplied by the carbohydrate content of that food.

A numerical system of measuring the rate of BLOOD GLUCOSE generation by a particular food item as compared to a reference item, such as glucose = 100. Foods with higher glycemic index numbers create greater blood sugar swings. These numbers do not correspond to calories or amounts of food intake but rather, depend on the rates of digestion and absorption of these food items.

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