Advertisement

Topics

Effect of an Extract of Green Tea on Adults With Type 2 Diabetes

2014-08-27 03:42:00 | BioPortfolio

Summary

The objective of this study was to determine if taking an extract of green tea for three months could improve glucose control in adults with diabetes.

Description

Background: Recent evidence suggests that tea from Camellia Senensis (e.g., green, oolong and black tea) may have a hypoglycemic effect.

Objective: We evaluated the ability of an extract of green and black tea to improve glucose control over a three month period using a double blinded randomized multiple dose (either placebo, 375mg or 750mg) study in adults in with Type 2 Diabetes.

Patients: The 49 subjects who completed this study were predominantly whites with an average age of 65, a median duration of Diabetes of 6 years, and 80% reported using hypoglycemic medication.

Measurements: HbA1c at three months was the primary endpoint. Results: After three months the mean changes in HbA1c were +0.4, +0.3 and +0.5, in the placebo, 375mg and 750mg arms, respectively. The changes were not significantly different between study arms.

Limitations: Evaluation of a particular extract that contained components of black teas as well as green tea. Power insufficient to detect changes in HbA1c < 0.5.

Conclusions: We did not find a hypoglycemic effect of extract of green tea in adults with Type 2 Diabetes, but cannot rule out the possibility that tea may have a small beneficial effect.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Diabetes

Intervention

Extract of Green and Black Tea

Location

Dartmouth-Hitchcock Medical Center
Lebanon
New Hampshire
United States
03756

Status

Completed

Source

Dartmouth-Hitchcock Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:42:00-0400

Clinical Trials [1760 Associated Clinical Trials listed on BioPortfolio]

Effect of Green Tea Extract on Type 2 Diabetes

The purpose of this study is to examine the effect of green tea extract (GTE) on type 2 diabetes and to explore the relationship between GTE and related hormone peptides.

The Effect of Green Tea or Cocoa Extracts in Endothelial Dysfunction in Patients With Diabetes Mellitus

The purpose of this study is to determine whether green tea or cocoa extracts are effective in improve endothelial dysfunction in patients with diabetes mellitus and nephropathy and arteri...

Green Tea Extract (Polyphenon E) in Preventing Cancer in Healthy Participants

RATIONALE: Green tea extract (Polyphenon E) contains ingredients that may prevent the development of cancer. PURPOSE: This phase I trial is studying how well green tea extract works in pr...

Green Tea Extract in Treating Patients With Nonmetastatic Bladder Cancer

RATIONALE: Green tea extract contains ingredients that may slow the growth of certain cancers. It is not yet known whether green tea extract is more effective than a placebo when given bef...

Green Tea, Decaffeinated Black Tea, or Water in Treating Patients With Prostate Cancer Undergoing Surgery

RATIONALE: Green tea contains ingredients that may prevent or slow the growth of certain cancers. It is not yet known whether green tea is more effective than decaffeinated black tea or wa...

PubMed Articles [7573 Associated PubMed Articles listed on BioPortfolio]

Maternal consumption of green tea extract during pregnancy and lactation alters offspring's metabolism in rats.

Green tea extract has anti-inflammatory and antioxidant effects which improve dyslipidemia and decrease adipose tissue depots associated with hyperlipidic diet consumption.

Effect of green tea extract supplementation on exercise-induced delayed onset muscle soreness and muscular damage.

Previous studies addressed the antioxidant and anti-inflammatory role of compounds from green tea in different human tissues. Positive antioxidant and anti-inflammatory effects were described for brai...

Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice.

The present study was aimed to investigate the effect of Urtica dioica Linn. (UD) extract against chronic diabetes mediated anxiogenic and depressive like behavior in mice. Streptozotocin (STZ) (50 ...

Remote Sensing Identification of Urban Black-Odor Water Bodies Based on High-Resolution Images:A Case Study in Nanjing.

The identification of urban black-odor water bodies plays an important role in monitoring and controlling black-odor water bodies. In 2016, a ground survey was conducted on the urban reach of Nanjing,...

Green tea consumption and risk of type 2 diabetes in Chinese adults: the Shanghai Women's Health Study and the Shanghai Men's Health Study.

Epidemiological evidence on the association between tea consumption and the risk of type 2 diabetes (T2D) is inconsistent. This study prospectively investigated whether green tea drinking affects the ...

Medical and Biotech [MESH] Definitions

A beverage made by FERMENTATION of black tea and/or green tea.

A dehydrated extract of thyroid glands. After the removal of fat and connective tissue, the extract is dried or lyophilized to yield a yellowish to buff-colored amorphous powder containing 0.17-0.23% of iodine.

Algae of the division Chlorophyta, in which the green pigment of CHLOROPHYLL is not masked by other pigments. Green algae have over 7000 species and live in a variety of primarily aquatic habitats. Only about ten percent are marine species, most live in freshwater. They are more closely related to the green vascular land PLANTS than any other group of algae.

Urination of a large volume of urine with an increase in urinary frequency, commonly seen in diabetes (DIABETES MELLITUS; DIABETES INSIPIDUS).

The thick green-to-black mucilaginous material found in the intestines of a full-term fetus. It consists of secretions of the INTESTINAL GLANDS; BILE PIGMENTS; FATTY ACIDS; AMNIOTIC FLUID; and intrauterine debris. It constitutes the first stools passed by a newborn.

More From BioPortfolio on "Effect of an Extract of Green Tea on Adults With Type 2 Diabetes"

Advertisement
Quick Search
Advertisement
Advertisement

 

Searches Linking to this Trial