Advertisement

Topics

Efficacy and Safety Study in the Treatment of Chronic Diabetic Foot Ulcers

2014-08-27 03:42:07 | BioPortfolio

Summary

The purpose of this study is to determine the safety and efficacy of Dermal-LSR plus Standard of Care (SOC) for the treatment of diabetic foot ulcers (DFU)in comparison to the treatment to SOC alone.

Description

The study is a pivotal, prospective, randomized, controlled, open-label, multi-center study that will evaluate the effectiveness and safety of topically applied Dermal-LSR in chronic DFUs.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Diabetic Foot Ulcer

Intervention

Dermal - Living Skin Replacement (Dermal - LSR)

Location

Southern Arizona Veterans Administration Health Care System, 3601 S. 6th Avenue (2-112)
Tuscon
Arizona
United States
85723

Status

Terminated

Source

ApoPharma

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:42:07-0400

Clinical Trials [3181 Associated Clinical Trials listed on BioPortfolio]

Efficacy and Safety Study of Dermal-Living Skin Replacement to Treat Diabetic Foot Ulcers

The purpose of this study is to test the efficacy and side effects, if any, of Dermal - LSR combined with standard treatment. We hypothesize the treatment will provide beneficial results ...

DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers

This is a prospective, multicenter, clinical research trial evaluating the clinical outcomes of DermACELL AWM in dermal regeneration.

Pilot Study to Assess the Quantitative Dermal Transfer Efficiencies of Solids for Multiple Transfer Pathways

Dermal transfer efficiency has been defined as the amount of material that moves from one surface to another following contact. The investigators propose to measure dermal transfer effici...

A Study With Primatrix Dermal Repair Scaffold For The Treatment Of Diabetic Foot Ulcers

The purpose of this study is to compare the clinical and economic effectiveness of PriMatrix and Standard of Care in the treatment of diabetic foot ulcers (DFUs) in subjects with controlle...

Dermal Thermometry and Self-Care of High Risk Diabetic Patients

Foot ulcers remain the most common reason for hospital admission among veterans with diabetes. Healing and preventing these wounds should be a high priority for clinicians treating these h...

PubMed Articles [9487 Associated PubMed Articles listed on BioPortfolio]

Novel insole design for diabetic foot ulcer management.

Around the world, over 400 million people suffer from diabetes. In a chronic diabetic condition, the skin underneath the foot often becomes extremely soft and brittle, resulting in the development o...

Incidence and Risk Factors of Diabetic Foot Ulcer: A Population-Based Diabetic Foot Cohort (ADFC Study)-Two-Year Follow-Up Study.

This study was carried out to assess the incidence and risk factors of diabetic foot ulcer (DFU).

Risk factors for diabetic foot ulcer recurrence: A prospective 2-year follow-up study in Egypt.

To determine the frequency of diabetic foot ulcer recurrence and its potential risk factors.

The Changes of Trends in the Diagnosis and Treatment of Diabetic Foot Ulcer over a 10-Year Period: Single Center Study.

This study aims to describe the trends in the severity and treatment modality of patients with diabetic foot ulcer (DFU) at a single tertiary referral center in Korea over the last 10 years and compar...

A randomized controlled trial comparing helium-neon laser therapy and infrared laser therapy in patients with diabetic foot ulcer.

This study aimed to compare the effects of (HNLT) and (ILT) on diabetic foot ulcer. Sixty-five patients with diabetic foot ulcer (51 males and 14 females) aged 50-60 years. The participants were clas...

Medical and Biotech [MESH] Definitions

Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.

Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.

Lesion on the surface of the skin of the foot, usually accompanied by inflammation. The lesion may become infected or necrotic and is frequently associated with diabetes or leprosy.

Benign DERMATOSIS caused by a loss of dermal ELASTIC TISSUE resulting in localized sac-like areas of flaccid skin. It can be either primary (idiopathic) or secondary to other skin conditions, PENICILLAMINE use, or premature birth.

The mechanical planing of the SKIN with sand paper, emery paper, or wire brushes, to promote reepithelialization and smoothing of skin disfigured by ACNE scars or dermal NEVI.

More From BioPortfolio on "Efficacy and Safety Study in the Treatment of Chronic Diabetic Foot Ulcers"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

Diabetes
Diabetes is a lifelong condition that causes a person's blood sugar level to become too high. The two main types of diabetes are: type 1 diabetes type 2 diabetes In the UK, diabetes affects approximately 2.9 million people. There are a...

Wound management
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...


Searches Linking to this Trial