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A Safety and Immunology Study of a DNA Trivalent Influenza Vaccine

2014-08-27 03:42:35 | BioPortfolio

Summary

The purpose of this study is to evaluate how well the vaccine is tolerated at sites where administrations are given and any effects it may have on subjects' wellbeing. The study will also test the ability of vaccine to cause particular immune responses in the body.

Description

Influenza is a contagious disease of the upper airways and the lungs. It rapidly spreads around the world in seasonal epidemics, killing hundreds of thousands of people and having high economic consequences due to healthcare costs and lost productivity. Each year governments recommend groups who are at risk of influenza or its complications to receive influenza vaccination. Current vaccine supply is not sufficient to meet the demand if this recommendation were to be taken up by all. This study is part of the clinical development of a particle mediated epidermal delivery (PMED) trivalent DNA vaccine for the prevention of influenza.This study will investigate the safety and tolerability of this vaccine as well as assess the humoral and cellular immunogenicity of the vaccine in healthy subjects.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention

Conditions

Influenza

Intervention

Trivalent DNA Vaccine (PIA0601) with or without DEI-LT (pPJV2012)

Location

Quintiles Lenexa (QLX)
Lenexa
Kansas
United States
66219

Status

Completed

Source

PowderMed

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:42:35-0400

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Medical and Biotech [MESH] Definitions

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