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Individual Versus Standard Follicle Stimulating Hormone Dose for Controlled Ovarian Stimulation and Insemination

2014-07-23 21:35:22 | BioPortfolio

Summary

The purpose of this study is to test if recombinant follicle stimulating hormone (rFSH) given in individual doses, according to a nomogram we have constructed based on our results from a previous study, results in more patients maturing 2-3 follicles compared to standard dose.

Study Design

Allocation: Randomized, Control: Dose Comparison, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Infertility

Intervention

rFSH drug dose

Location

The Fertility Clinic, dep.4071, Copenhagen University Hospital, Rigshospitalet
Copenhagen East
Denmark
2100

Status

Active, not recruiting

Source

Rigshospitalet, Denmark

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:35:22-0400

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Medical and Biotech [MESH] Definitions

The relationship between the dose of an administered drug and the response of the organism to the drug.

The ratio of the dose that produces toxicity to the dose that produces a clinically desired or effective response.

Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.

The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.

Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.

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