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Effects of Insufflated Gas on Core Temperature and Post-operative Pain During Laparoscopic Surgery

2014-07-24 14:23:59 | BioPortfolio

Summary

During laparoscopy, administration of cold and dry carbon dioxide (CO2) leads to hypothermia. Different types of gas conditioning have been studied in order to prevent this specific hypothermia. Intra-abdominal administration of local anesthetics has also been studied in order to prevent post-operative pain. In both cases, some results have been described.

The investigators propose to evaluate in a prospective, randomized, double blind trial, the impact of 4 different types of conditioning of insufflated gas during laparoscopy for womb surgery on hypothermia prevention and post-operative pain. These 4 types of gas conditioning are:

- CO2 wet and warm with nebulized ropivacaïne

- CO2 wet and warm without nebulized ropivacaïne

- CO2 dry and cold with nebulized ropivacaïne

- CO2 dry and cold without nebulized ropivacaïne

The investigators use a new device (Aeroneb® Pro [Aerogen® Company]) which can wet (by nebulization) the insufflated gas and therefore permits intraperitoneal medicament administration (local anesthetics).

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention

Conditions

Laparoscopy

Intervention

ropivacaïne 0.75% (Naropeine), womb operation by laparoscopy, Aeroneb® Pro (Aerogen® Company)

Location

Sihcus-Cmco
Schiltigheim
France
67300

Status

Recruiting

Source

University Hospital, Strasbourg, France

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:23:59-0400

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