Advertisement

Topics

Effects of Insufflated Gas on Core Temperature and Post-operative Pain During Laparoscopic Surgery

2014-07-24 14:23:59 | BioPortfolio

Summary

During laparoscopy, administration of cold and dry carbon dioxide (CO2) leads to hypothermia. Different types of gas conditioning have been studied in order to prevent this specific hypothermia. Intra-abdominal administration of local anesthetics has also been studied in order to prevent post-operative pain. In both cases, some results have been described.

The investigators propose to evaluate in a prospective, randomized, double blind trial, the impact of 4 different types of conditioning of insufflated gas during laparoscopy for womb surgery on hypothermia prevention and post-operative pain. These 4 types of gas conditioning are:

- CO2 wet and warm with nebulized ropivacaïne

- CO2 wet and warm without nebulized ropivacaïne

- CO2 dry and cold with nebulized ropivacaïne

- CO2 dry and cold without nebulized ropivacaïne

The investigators use a new device (Aeroneb® Pro [Aerogen® Company]) which can wet (by nebulization) the insufflated gas and therefore permits intraperitoneal medicament administration (local anesthetics).

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention

Conditions

Laparoscopy

Intervention

ropivacaïne 0.75% (Naropeine), womb operation by laparoscopy, Aeroneb® Pro (Aerogen® Company)

Location

Sihcus-Cmco
Schiltigheim
France
67300

Status

Recruiting

Source

University Hospital, Strasbourg, France

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:23:59-0400

Clinical Trials [353 Associated Clinical Trials listed on BioPortfolio]

Pain Relief by Intra-Peritoneal Ropivacaine During Gynecological Laparoscopy

In our prospective, randomized, placebo controlled and double-blinded study we will study the efficacy of intraperitoneal ropivacaine nebulization on pain relief during gynecological lapar...

Gut Oxygenation and Laparoscopy

Patients with left-colon cancer will be randomized to laparoscopic or laparotomic operation. during surgery and for 6 days after operation, intestinal oxygen tension and ischemia-reperfusi...

Aerogen Nebuliser Versus Standard Nebulised Therapy in Acute Chronic Obstructive Pulmonary Disease

The investigators are looking at whether a new type of nebuliser (a machine used to deliver drugs to the airways) is better at delivering drugs to the lungs of people with Chronic Obstruct...

Effectiveness of the Aeroneb in Acute Severe Asthma

Background: The bronchodilator therapy is an essential component of the management of asthma exacerbation. The delivery of bronchodilators to the lungs in asthma exacerbations is usually a...

2-D and 3-D Laparoscopic Hysterectomy

Background: No randomised trials have been conducted, and only a single retrospective study exists comparing 3D and 2D laparoscopic hysterectomy. In that study, operative time for h...

PubMed Articles [1458 Associated PubMed Articles listed on BioPortfolio]

A description of externally recorded womb sounds in human subjects during gestation.

Reducing environmental noise benefits premature infants in neonatal intensive care units (NICU), but excessive reduction may lead to sensory deprivation, compromising development. Instead of minimal n...

Single port laparoscopy (SPL): Retrospective study evaluating postoperative pain in comparison with conventional laparoscopy (CL).

To compare postoperative pain after single port laparoscopy (SPL) approach with conventional laparoscopy (CL) in case of adnexectomy.

Value of diagnostic and therapeutic laparoscopy for patients with blunt abdominal trauma: A 10-year medical center experience.

Laparoscopy has been used for the diagnosis and treatment for hemodynamically stable patients with penetrating abdominal trauma. This study evaluated whether diagnostic and therapeutic laparoscopy can...

Using a Mobile Smartphone to Perform Laparoscopy.

Laparoscopy has gradually expanded its use in gynecologic surgery over the last three decades. In this report, a new laparoscopic setup is presented using a mobile smartphone that allows for a low-cos...

Comparison of outcomes of laparoscopy-assisted and open proximal gastrectomy with jejunal interposition for early gastric cancer in the upper third of the stomach: A retrospective observational study.

Laparoscopy-assisted proximal gastrectomy with jejunal interposition (LAPG-JI) is not yet widely used because the three anastomotic procedures involved in this operation are technically complicated. T...

Medical and Biotech [MESH] Definitions

A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.

Placement of one of the surgeon's gloved hands into the ABDOMINAL CAVITY to perform manual manipulations that facilitate the laparoscopic procedures.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

Any operation on the spinal cord. (Stedman, 26th ed)

A plastic operation on the esophagus. (Dorland, 28th ed)

More From BioPortfolio on "Effects of Insufflated Gas on Core Temperature and Post-operative Pain During Laparoscopic Surgery"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Anesthesiology
An anesthesiologist (US English) or anaesthetist (British English) is a physician trained in anesthesia and perioperative medicine. Anesthesiologists are physicians who provide medical care to patients in a wide variety of (usually acute) situations. ...


Searches Linking to this Trial