A Study to Determine if BOL-303224 is Safe and Effective in the Treatment of Bacterial Conjunctivitis.

2014-07-23 21:43:16 | BioPortfolio


Evaluation of the clinical and microbial efficacy of BOL-303224, compared to vehicle in the treatment of bacterial conjunctivitis.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Acute Bacterial Conjunctivitis


BOL-303224, Vehicle




Bausch & Lomb, Inc.

Results (where available)

View Results


Published on BioPortfolio: 2014-07-23T21:43:16-0400

Clinical Trials [778 Associated Clinical Trials listed on BioPortfolio]

A Study to Investigate the Safety and Efficacy of BOL-303224 in the Treatment of Bacterial Conjunctivitis

This is a study to investigate a novel drug candidate for the treatment of bacterial conjunctivitis.

Evaluation of Clinical and Microbial Efficacy and Safety of AzaSite Compared to Vehicle for Bacterial Conjunctivitis

The purpose of this study is to evaluate the clinical and microbial efficacy and safety of AzaSite compared to vehicle for bacterial conjunctivitis. Adults and children one year of age and...

FST-100 in the Treatment of Acute Viral Conjunctivitis

This randomized, double masked, multi-center study is being conducted to support the safety and efficacy of FST-100 for the treatment of acute viral conjunctivitis. The study intends to sh...

Clinical and Microbial Efficacy of ISV403 in Bacterial Conjunctivitis

To evaluate the clinical and microbial efficacy of ISV-403 administered three times a day for 5 days compared to vehicle three times a day for 5 days in the treatment of bacterial conjunct...

Moxifloxacin AF Ophthalmic Solution for Treatment of Bacterial Conjunctivitis

The purpose of this study is to evaluate the safety and efficacy of Moxifloxacin AF Ophthalmic Solution compared to Moxifloxacin AF Vehicle in the treatment of bacterial conjunctivitis in ...

PubMed Articles [10162 Associated PubMed Articles listed on BioPortfolio]

Antibodies to Conserved Surface Polysaccharides Protect Mice Against Bacterial Conjunctivitis.

Bacterial conjunctivitis is a major problem in ocular health. Little is known about protective immune effectors in the conjunctiva. We evaluated whether opsonic antibody to the conserved surface/capsu...

Alcaftadine 0.25% versus Olopatadine 0.1% in Preventing Cedar Pollen Allergic Conjunctivitis in Japan: A Randomized Study.

To compare alcaftadine and olopatadine ophthalmic solutions, and vehicle for preventing allergen-mediated conjunctivitis in Japanese subjects.

Brinzolamide-induced Follicular Conjunctivitis.

We report a case of a patient who developed a severe case of follicular conjunctivitis from brinzolamide after 1.5 years of consistent use. This patient was re-challenged again after resolution of the...

Acute Bacterial Meningitis.

While acute bacterial meningitis is becoming less common in developed countries because of the widespread use of vaccines against Streptococcus pneumoniae, Neisseria meningitides, and Haemophilus infl...

Antibiotic Recommendations for Acute Otitis Media and Acute Bacterial Sinusitis: Conundrum No More.

There has been a substantial change in the prevalence and microbiologic characteristics of cases of acute otitis media secondary to the widespread use of pneumococcal conjugate vaccines. Current trend...

Medical and Biotech [MESH] Definitions

A highly contagious disease characterized by subconjunctival hemorrhage, sudden swelling of the eyelids and congestion, redness, and pain in the eye. Epidemic conjunctivitis caused by Enterovirus 70 (EV-70) was first described in Africa in 1969. It is caused also by Coxsackievirus A24 variant (CA24v). Epidemics by this organism have appeared most frequently in Asia.

Conjunctivitis due to hypersensitivity to various allergens.


Purulent infections of the conjunctiva by several species of gram-negative, gram-positive, or acid-fast organisms. Some of the more commonly found genera causing conjunctival infections are Haemophilus, Streptococcus, Neisseria, and Chlamydia.

Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.

More From BioPortfolio on "A Study to Determine if BOL-303224 is Safe and Effective in the Treatment of Bacterial Conjunctivitis."

Quick Search


Relevant Topic

The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...

Searches Linking to this Trial