A Trial to Evaluate the Shedding and Safety of CAIV-T
Summary
The primary objective of this study is:
- to describe the proportion of individuals who shed vaccine strain viruses.
Description
The secondary objectives of this study are:
- To describe the duration of shedding of vaccine viruses
- To quantitate shed vaccine viruses
- To describe the genotypic and phenotypic stability of shed vaccine viruses
- To describe the safety and tolerability of CAIV-T
- To describe the safety and tolerability of CAIV-T in relation to shedding
Study Design
Allocation: Non-Randomized, Control: Active Control, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Conditions
Healthy
Intervention
CAIV-T Vaccine
Location
Little Rock Allergy & Asthma Clinic, PA
Little Rock
Arkansas
United States
72205
Status
Completed
Source
MedImmune LLC
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00344305
- Information obtained from ClinicalTrials.gov on July 15, 2010
Published on BioPortfolio: 2014-08-27T03:43:49-0400
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Medical and Biotech [MESH] Definitions
Diphtheria-tetanus Vaccine
A combined vaccine used to prevent infection with diphtheria and tetanus toxoid. This is used in place of DTP vaccine (DIPHTHERIA-TETANUS-PERTUSSIS VACCINE) when PERTUSSIS VACCINE is contraindicated.
Poliovirus Vaccine, Oral
A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)
Brucella Vaccine
A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.
Mumps Vaccine
A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.
Measles Vaccine
A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)
