Melatonin Treatment and Inflammation, Oxidative Stress and Autonomic Function in Connection With Surgery

2014-07-23 21:45:22 | BioPortfolio


The purpose of this study is to determine whether treatment with melatonin can reduce cell damage and inflammation in connection with laparoscopic gall bladder surgery.


Laparoscopic gall bladder surgery is connected with changes in the body resulting in cell damage and inflammation. Melatonin is a hormone produced in brain and regulate sleep rhythm, temperature, production of other hormones and function of organs. Furthermore melatonin can modify cell damage and inflammation. After surgery the production of melatonin is disturbed. The purpose of this study is therefore to determine whether treatment with melatonin can reduce cell damage and inflammation in connection with laparoscopic gall bladder surgery.

Study Design

Allocation: Random Sample, Time Perspective: Cross-Sectional, Time Perspective: Prospective


Oxidative Stress


Melatonin (drug), Laktose


Department of Surgical Gastroenterology, University Hospital of Copenhagen in Gentofte


Not yet recruiting


University Hospital, Gentofte, Copenhagen

Results (where available)

View Results


Published on BioPortfolio: 2014-07-23T21:45:22-0400

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