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This is a comparative, pre-post study of the non-pneumatic anti-shock garment (NASG) to establish its effectiveness in reducing maternal mortality and morbidity due to obstetrical hemorrhage. The sites are two maternity teaching hospitals in Egypt: El Galaa, in Cairo and Assiut University in Assiut.
There are two Main Aims:
Aim 1: To test the efficacy of the NASG on women suffering from obstetric hemorrhage as compared to hemorrhaging women who do not receive the NASG. Our primary outcomes are mortality and severe morbidity. Secondary outcomes include: a) decreased blood loss due to obstetric hemorrhage, b) fewer emergency hysterectomies, and c) more rapid recovery from shock in the intervention group as compared to the control group.
Aim 2: Using the same study design, to examine side effects that might be associated with NASG use, including a) decreased urine output, b) hypoxia, dyspnea, or other form of respiratory distress, c) nausea and vomiting in the intervention group as compared to the control group.
Allocation: Non-Randomized, Control: Historical Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
non-pneumatic anti-shock garment (NASG)
Assuit University Hospital
University of California, San Francisco
Published on BioPortfolio: 2014-08-27T03:45:36-0400
This trial will address the question of whether early application of the Non-pneumatic Anti-Shock Garment (NASG) at the Satellite Health Facility (SHF) level before transport to a Referral...
Study comparing different groups of people and how they respond to application of the non-pneumatic anti-shock garments. Investigators will divide all recruited participants into three gro...
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An abnormally low volume of blood circulating through the body. It may result in hypovolemic shock (see SHOCK).
A family of heat-shock proteins that contain a 70 amino-acid consensus sequence known as the J domain. The J domain of HSP40 heat shock proteins interacts with HSP70 HEAT-SHOCK PROTEINS. HSP40 heat-shock proteins play a role in regulating the ADENOSINE TRIPHOSPHATASES activity of HSP70 heat-shock proteins.
Shock produced as a result of trauma.
A subfamily of small heat-shock proteins that are closely related to ALPHA B-CRYSTALLIN. Hsp20 heat-shock proteins can undergo PHOSPHORYLATION by CYCLIC GMP-DEPENDENT PROTEIN KINASES.
Shock resulting from diminution of cardiac output in heart disease.
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Obstetrics and gynaecology
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