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A Study of Two Iodinated Contrast Agents in Renally Impaired Patients Undergoing Cardiac Angiography

2014-08-27 03:46:15 | BioPortfolio

Summary

The main purpose of this study is to compare the incidence of contrast induced nephrotoxicity following the administration of Isovue or Visipaque in patients with moderate to severe renal insufficiency undergoing cardiac angiography. Serum creatinine will be measured before and up to 48-72 hours after the administration of the contrast agent to evaluate renal function.

Study Design

Allocation: Randomized, Control: Active Control, Intervention Model: Parallel Assignment, Masking: Double-Blind

Conditions

CIN

Intervention

Iopamidol 370 mgI/mL

Location

Bracco Diagnostics, Inc
Princeton
New Jersey
United States

Status

Completed

Source

Bracco Diagnostics, Inc

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:46:15-0400

Clinical Trials [9 Associated Clinical Trials listed on BioPortfolio]

Renal Safety of Iopamidol vs. Iodixanol During Coronary Angiography in Diabetic Patients

The purpose of this study is to compare the incidence of contrast-induced nephropathy (CIN) following the administration of iopamidol-370 (Iopamiro-370) and iodixanol-320 (Visipaque 320) i...

Patients With Renal Impairment and Diabetes Undergoing Computed Tomography (CT)

The main purpose of this study is to compare the incidence of contrast induced nephrotoxicity following the administration of Isovue (iopamidol) or Visipaque in diabetic patients with mode...

Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Computed Tomography

It is well known that X-ray contrast media can affect kidney function in some patients, especially when administered intra-arterially, and patients who already suffer from reduced kidney f...

Isovue in Peripheral Digital Subtraction Angiography

No significant differences in observed motion artifacts or pain reported during peripheral DSA performed for diagnostic and/or endovascular therapeutic purposes.

Kidney Damage In Patients With Severe Fall In eGFR

This is a pilot study using a randomized, double blinded, comparison of two iodinated contrast agents used during percutaneous coronary intervention (PCI). All patients enrolled must have ...

PubMed Articles [5 Associated PubMed Articles listed on BioPortfolio]

Electrochemical reductive dehalogenation of iodine-containing contrast agent pharmaceuticals: Examination of reactions of diatrizoate and iopamidol using the method of rotating ring-disc electrode (RRDE).

This study examined the electrochemical (EC) reduction of iodinated contrast media (ICM) exemplified by iopamidol and diatrizoate. The method of rotating ring-disc electrode (RRDE) was used to elucida...

Nephrotoxicity of iodixanol versus iopamidol in patients undergoing peripheral angiography with or without endovascular therapy.

To compare the nephrotoxic effects of iodixanol and iopamidol in patients undergoing peripheral angiography.

Oxidation of iopamidol with ferrate (Fe(VI)): Kinetics and formation of toxic iodinated disinfection by-products.

Presence of iodinated X-ray contrast media (ICMs) in source water is of high concern, because of their potential to form highly toxic iodinated disinfection by-products (I-DBPs). This study investigat...

Comparison of three computed tomographic angiography protocols to assess diameters of major arteries in African grey parrots (Psittacus erithacus).

OBJECTIVE To evaluate 3 contrast medium infusion (CMI) protocols for CT angiography (CTA) and measurement of major artery diameters in African grey parrots (Psittacus erithacus). ANIMALS 9 African gre...

A human endogenous protein exerts multi-role biomimetic chemistry in synthesis of paramagnetic gold nanostructures for tumor bimodal imaging.

Protein-mediated biomimetic nanoparticles because of simplicity of their synthesis, subdued nonspecific adsorption, improved pharmacokinetics, and biocompatibility have been receiving increasing atten...

Medical and Biotech [MESH] Definitions

A non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures.

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