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High Dose Simplified Folfiri in Advanced Colorectal Cancer: a Multicentre Phase II Study

2014-07-23 21:46:19 | BioPortfolio

Summary

A multicentre phase II study to evaluate the results of high dose simplified folfiri in advanced colorectal cancer

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Advanced Colorectal Cancer

Intervention

Administration of high dose simplified folfiri

Location

University Hospital Ghent
Ghent
Belgium
9000

Status

Completed

Source

University Hospital, Ghent

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:46:19-0400

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Medical and Biotech [MESH] Definitions

Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with the formation of colorectal cancer (MCC stands for mutated in colorectal cancer).

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