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Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer

2014-07-24 14:25:50 | BioPortfolio

Summary

RATIONALE: Learning about the effects of chemotherapy and biological therapy on nerve function may help doctors plan treatment and help patients live more comfortably.

PURPOSE: This clinical trial is studying peripheral neuropathy in patients who are receiving chemotherapy or biological therapy for cancer.

Description

OBJECTIVES:

- Determine the change in peripheral nerve function in cancer patients during and after treatment with chemotherapy or biologic therapy.

- Determine the clinical measurement of hearing-related air and bone conduction and vibratory sensation in these patients.

- Correlate the changes in orthostatic blood pressure using both the Vasotrac automated blood pressure device and the standard clinical automated blood pressure equipment.

- Determine the patient's perception of hearing quality before and after treatment with chemotherapy or biologic therapy.

OUTLINE: This is a multicenter study.

Patients undergo a 1-hour peripheral nerve function assessment, including hearing, vibratory sensation, and blood pressure testing, at baseline and then at 4, 8, and 12 weeks during treatment with chemotherapy or biologic therapy.

PROJECTED ACCRUAL: A total of 20 patients will be accrued for this study.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Neurotoxicity

Intervention

management of therapy complications

Location

Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center
Cleveland
Ohio
United States
44106-5065

Status

Completed

Source

Case Comprehensive Cancer Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:25:50-0400

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