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TNF Alpha in Refractory Asthma

2014-08-27 03:46:45 | BioPortfolio

Summary

The purpose of this study was to investigate whether the administration of etanercept to patients with severe asthma improved their asthma related quality of life and a measure of the degree of reactivity of the airways

Description

Although steroid dependent asthma represents a small population of patients with asthma, they consume a disproportionately large amount of the health resource burden attributed to asthma. Treatment options in this group are extremely limited; the development of effective treatments for this group of patients should be a priority, not only for increasing individual patient quality of life but for long term reduction of health spending.

This randomised, double blind, placebo controlled, cross over trial will investigate the efficacy of a soluble TNF receptor, etanercept, in severe, steroid dependant asthma.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Asthma

Intervention

Etanercept

Location

Institute for Lung Health
Leicester
Leicestershire
United Kingdom
LE3 9QP

Status

Completed

Source

University Hospitals, Leicester

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:46:45-0400

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Medical and Biotech [MESH] Definitions

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Drugs that are used to treat asthma.

A beta-adrenergic agonist used in the treatment of asthma and bronchospasms.

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