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More specifically the effects on the following parameters will be assessed:
- Vitamin D metabolites.
- Parathyroid hormone.
- Bone turnover.
- Bone mineral accretion.
- Serum calcium and phosphate.
- Renal handling of calcium and phosphate.
This work package will consist of a randomised double blind one-year vitamin D supplementation study. Primary effect parameter is change in bone mineral content and therefore study duration will be one year. A total of 225 subjects, 75 in each of the three groups: one control and two intervention groups, will be included Two dosages of supplementation will be used: 5 µg per day and 10 µg per day.
Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention
Vitamin D Deficiency
cholecalciferol (D3) (vitamin)
Department of Human Nutrition, The Royal Veterinary and Agricultural University
University of Copenhagen
Published on BioPortfolio: 2014-08-27T03:47:05-0400
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