Advertisement

Topics

Study With Rupatadine in Mosquito-Bite Allergic Adult Subjects

2014-07-23 21:46:56 | BioPortfolio

Summary

The study will find out how effective rupatadine is in the treatment of mosquito bite symptoms in adult patients allergic to mosquito bites.

Description

Mosquito-bite symptoms include wheals and pruritic bite papules. Oral antihistamines have shown to decrease whealing ang accompanying pruritus in placebo-controlled trials.

Subjects will be treated for 4 days, and exposed to experimental mosquito bite at day 3.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Prevention

Conditions

Allergy

Intervention

Rupatadine, Placebo

Location

Ulappatorin Lääkäriasema
Espoo
Finland
33101

Status

Not yet recruiting

Source

J. Uriach and Company

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:46:56-0400

Clinical Trials [251 Associated Clinical Trials listed on BioPortfolio]

Efficacy of Rupatadine 5, 10 and 20 Mg in Chronic Idiopathic Urticaria

The objective of this study is to evaluate the efficacy and safety of rupatadine for the treatment of CIU symptoms.To assess the clinical efficacy of a dose ranging of rupatadine fumarate ...

Chronic Urticaria - Long Term Assessment of Effects of Rupatadine

To compare CSU disease activity at the end of the follow up phase between patients that had been treated daily continuously vs. on-demand in the treatment phase

Efficacy and Safety of Rupatadine 10 and 20 Mg in Chronic Idiopathic Urticaria

· To evaluate the efficacy of rupatadine 10 and 20 mg for the treatment of CIU symptoms over four-week treatment period in comparison with placebo.

Evaluation of Possible Effects on the QT/ QTc Interval of Rupatadine in Healthy Volunteers

This phase I trial will evaluate the effects of rupatadine, at a dose of 10 mg OD (authorised and marketed dose) and the 100mg/day (supratherapeutic dose) on the ECG parameters with a spec...

Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy

The purpose of this research study is to find out if cat allergy shots with combination with AMG 157, an experimental medication, will help the cat allergy shots work after just one year o...

PubMed Articles [1728 Associated PubMed Articles listed on BioPortfolio]

Association of stat6 gene variants with food allergy diagnosed by double-blind placebo-controlled food challenges.

This study describes the role of two STAT6 gene variants in food allergy using data of patients and their parents who underwent double-blind placebo-controlled food challenges (DBPCFCs). After quality...

Efficacy and safety of five-day challenge for the evaluation of non-severe amoxicillin allergy in children.

Penicillin allergy is the most frequent drug allergy, among which aminopenicillins are reputed for causing delayed rashes in children, particularly in the context of viral infections. Despite a negati...

The Genetics of Food Allergy.

Food allergy likely arises from a complex interplay between environmental triggers and genetic susceptibility. Here, we review recent studies that have investigated the genetic pathways and mechanisms...

The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.

Antibiotic allergy labeling is highly prevalent and negatively impacts patient outcomes and antibiotic appropriateness. Reducing the prevalence and burden of antibiotic allergies requires the engageme...

Phenotypes and endotypes of food allergy: a path to better understanding the pathogenesis and prognosis of food allergy.

Medical and Biotech [MESH] Definitions

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.

A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder.

A method of treating an ALLERGY by administering ALLERGENS, in liquid formulation or tablets, to the ORAL MUCOSA under the tongue.

A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

More From BioPortfolio on "Study With Rupatadine in Mosquito-Bite Allergic Adult Subjects"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Allergies
The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...


Searches Linking to this Trial