Effect of Salicylate on Glucose Metabolism in Insulin Resistance States

2014-07-24 14:26:17 | BioPortfolio


We believe that diet induced obesity leads to activation of the IKK/NF-kB inflamatory pathway and that chronic inflammation leads to insulin resistance and diabetes. In rodents, salicylates inhibit IKK/NF-kB and may improve insulin sensitivity. We will study if this is true in people.

Study Design

Allocation: Randomized, Control: Placebo Control, Intervention Model: Parallel Assignment, Masking: Double-Blind


Insulin Resistance






Joslin Diabetes Center

Results (where available)

View Results


Published on BioPortfolio: 2014-07-24T14:26:17-0400

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