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Outpatient Registry Trial of Respiratory Tract Infections in Adults

2014-08-27 03:47:58 | BioPortfolio

Summary

To measure the speed of bacterial eradication from the respiratory tract after administration of azithromycin or telithromycin.

Description

To Evaluate the relationship between rate of S. pneumoniae killing in sputum, PK/PD, and clinical response of oral telithromycin and azithromycin in patients with AECB or CAP and to determine if there is a difference in the rates of infection site bacterial killing (as described above) between these 3 antibiotics against penicillin- and erythromycin-resistant S.pneumoniae

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Pneumonia, Bacterial

Intervention

azithromycin, telithromycin, Clarythromycin

Location

Western Kentucky Pulmonary Clinic
Louisville
Kentucky
United States
42240

Status

Terminated

Source

CPL Associates

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:47:58-0400

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Medical and Biotech [MESH] Definitions

Inflammation of the lung parenchyma that is caused by bacterial infections.

Pneumonia caused by infection with bacteria of the family RICKETTSIACEAE.

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Severe complication of pneumonia characterized by liquefaction of lung tissue.

A species of the genus PNEUMOVIRUS causing pneumonia in mice.

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