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Safety and Efficacy of a Novel Malathion Formulation in the Treatment of Head Lice

2014-07-23 21:47:19 | BioPortfolio

Summary

Current treatments for head lice include over-the-counter products such as permethrin and prescription products such as OVIDE (malathion 0.5%) lotion. In a previous phase II study, a novel, easy-to-use malathion 0.5% formulation was found to be a safe treatment for head lice. The current study will compare the efficacy and safety of this novel formulation of malathion with OVIDE and with an over-the-counter permethrin product.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Conditions

Lice Infestations

Intervention

MALG, Ovide (malathion) lotion 0.05%, Permethrin 1%

Location

Scottsdale
Arizona
United States

Status

Completed

Source

Taro Pharmaceuticals USA

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:47:19-0400

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Medical and Biotech [MESH] Definitions

A pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.

A general name for small, wingless, parasitic insects, previously of the order Phthiraptera. Though exact taxonomy is still controversial, they can be grouped in the orders ANOPLURA (sucking lice), MALLOPHAGA (biting lice), and Rhynchophthirina (elephant-lice).

An order of small, wingless parasitic insects, commonly known as lice. The suborders include ANOPLURA (sucking lice); AMBLYCERA; ISCHNOCERA; and Rhynchophthirina (elephant and warthog lice).

Parasitic attack or subsistence on the skin by members of the order Phthiraptera, especially on humans by Pediculus humanus of the family Pediculidae. The hair of the head, eyelashes, and pubis is a frequent site of infestation. (From Dorland, 28th ed; Stedman, 26th ed)

Infestations with arthropods of the subclass ACARI, superorder Acariformes.

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