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Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder

2014-08-27 03:49:22 | BioPortfolio

Summary

Patients with major depressive disorder (MDD) commonly have many gastrointestinal complaints. Gastrointestinal pain is classified into 2 categories: visceral and somatic pain. The main aim of this study is to compare somatic and visceral sensitivity between healthy people and pateints with MDD. These two sensitivities will be assessed by the 2 following tests: standardized rectal distension and Transdermal transcutaneous electric nerve stimulation. Thereafter, patients with MDD will be randomly allocated to escitalopram or reboxetine. After 6 weeks of treatment, somatic and visceral sensitivity will be reassessed.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Major Depression

Intervention

escitalopram, Reboxetine, No intervention

Location

Hospital Universitari vall d'Hebron
Barcelona
Catalonia
Spain
08036

Status

Recruiting

Source

Hospital Universitari Vall d'Hebron Research Institute

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:49:22-0400

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Medical and Biotech [MESH] Definitions

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