Determination of Gentamicin Dosing in Neonatal Patients

2014-07-23 21:48:09 | BioPortfolio


The purpose of this study is to determine what dosage of gentamicin for use in one-time administration device (Uniject) is appropriate.


This study aims to verify dosages of gentamicin for use in Uniject, chosen based on a consideration of gentamicin pharmacokinetics, safety, efficacy, target population body weight, cost, feasibility and acceptability.

Study Design

Allocation: Non-Randomized, Control: Dose Comparison, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment




Gentamicin in Uniject Pre-filled syringe


Dhaka Shishu Hospital


Active, not recruiting


Johns Hopkins Bloomberg School of Public Health

Results (where available)

View Results


Published on BioPortfolio: 2014-07-23T21:48:09-0400

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Medical and Biotech [MESH] Definitions

Antibiotic produced by Micromonospora inyoensis. It is closely related to gentamicin C1A, one of the components of the gentamicin complex (GENTAMICINS).

A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)

Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.

Semisynthetic 1-N-ethyl derivative of SISOMYCIN, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity.

The administration of substances into the eye with a hypodermic syringe.

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