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Comparison of Telavancin and Vancomycin for Complicated Skin and Skin Structure Infections With a Focus on Methicillin-resistant Staphylococcus Aureus

2014-08-27 03:54:04 | BioPortfolio

Summary

Study 0017 compares the safety and effectiveness of an investigational drug, telavancin, and an approved drug, vancomycin, for the treatment of complicated skin and skin structure infections.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Staphylococcal Skin Infection

Intervention

Telavancin, Vancomycin

Location

Paradise Valley Hospital, 2400 E. 4th Street
National City
California
United States
91950

Status

Completed

Source

Theravance

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:54:04-0400

Clinical Trials [1214 Associated Clinical Trials listed on BioPortfolio]

Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)

Serious infections caused by resistant bacteria are becoming more of a medical problem throughout the world. One of the ways to deal with this problem is to develop new drugs that can con...

Telavancin (TD 6424, ARBELIC™) for Treatment of Uncomplicated Staphylococcus Aureus Bacteremia

The purpose of this study is to determine whether telavancin (TD-6424, ARBELIC) can be safety administered to patients with bloodstream infections and whether telavancin is effective in tr...

TD-1792 in Gram-positive Complicated Skin and Skin Structure Infection

The purpose of this study is to determine whether TD-1792 is safe and effective when used to treat complicated skin and skin structure infections caused by Gram-positive bacteria.

Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant Staphylococcus Aureus

Study 0019 (NCT00124020) compares the safety and effectiveness of an investigational drug, telavancin, with vancomycin for the treatment of hospital-acquired pneumonia.

Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant Staphylococcus Aureus

Study 0015 (NCT00107952) compares the safety and effectiveness of an investigational drug, telavancin, with vancomycin for the treatment of hospital-acquired pneumonia.

PubMed Articles [9182 Associated PubMed Articles listed on BioPortfolio]

Multiple neonatal Staphylococcal cold abscesses in large skin folds: a benign neonatal skin infection.

Huber et al. previously reported 3 cases of a benign neonatal skin abscess named multiple neonatal staphylococcal cold abscesses of the large skin folds (MNSCA). Such cases have not been reported sin...

Bactericidal activity of Gallium-doped chitosan coatings against staphylococcal infection.

This study was to develop a new class of Gallium (Ga)-doped Chitosan (CS) coatings fabricated by electrophoretic deposition (EPD) that promise new opportunities in staphylococcal infection therapy.

Staphylococcus aureus enterotoxins modulate IL-22-secreting cells in adults with atopic dermatitis.

Atopic dermatitis (AD) is a chronic inflammatory immune-mediated skin disease characterized by skin colonization by Staphylococcus aureus. Interleukin (IL)-22, in cooperation with IL-17, triggers anti...

Fulminant Staphylococcal Infections.

Fulminant staphylococcal infection indicates an explosive, intense, and severe infection occurring in a patient whose previous condition and antecedent would never have caused any anticipation of life...

Epidemiology of Staphylococcal Scalded Skin Syndrome in United States Adults.

Medical and Biotech [MESH] Definitions

Strains of the genus Enterococcus that are resistant to the antibiotic VANCOMYCIN. The enterococci become resistant by acquiring plasmids carrying genes for VANCOMYCIN RESISTANCE.

Infections to the skin caused by bacteria of the genus STAPHYLOCOCCUS.

Poisoning by staphylococcal toxins present in contaminated food.

Abscess of the PSOAS MUSCLES resulting usually from disease of the lumbar vertebrae, with the pus descending into the muscle sheath. The infection is most commonly tuberculous or staphylococcal.

A disease of infants due to group 2 phage type 17 staphylococci that produce an epidermolytic exotoxin. Superficial fine vesicles and bullae form and rupture easily, resulting in loss of large sheets of epidermis.

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