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Green Tea Extract (Polyphenon E) in Preventing Cancer in Healthy Participants

2014-08-27 03:54:04 | BioPortfolio

Summary

RATIONALE: Green tea extract (Polyphenon E) contains ingredients that may prevent the development of cancer.

PURPOSE: This phase I trial is studying how well green tea extract works in preventing cancer in healthy participants.

Description

OBJECTIVES:

Primary

- Determine the effect of green tea extract (Polyphenon E) on cytochrome P450 enzyme activities and glutathione S-transferase activities and levels in healthy participants.

Secondary

- Determine the safety and tolerability of this drug in these participants.

OUTLINE: This is an open-label study.

Participants receive oral green tea extract (Polyphenon E) once daily for 4 weeks in the absence of unacceptable toxicity.

Participants are followed for 2 weeks.

PROJECTED ACCRUAL: A total of 44 participants will be accrued for this study.

Study Design

Masking: Open Label, Primary Purpose: Prevention

Conditions

Unspecified Adult Solid Tumor, Protocol Specific

Intervention

defined green tea catechin extract

Location

Arizona Cancer Center at University of Arizona Health Sciences Center
Tucson
Arizona
United States
85724

Status

Completed

Source

University of Arizona

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:54:04-0400

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