Green Tea Extract (Polyphenon E) in Preventing Cancer in Healthy Participants

2014-08-27 03:54:04 | BioPortfolio


RATIONALE: Green tea extract (Polyphenon E) contains ingredients that may prevent the development of cancer.

PURPOSE: This phase I trial is studying how well green tea extract works in preventing cancer in healthy participants.




- Determine the effect of green tea extract (Polyphenon E) on cytochrome P450 enzyme activities and glutathione S-transferase activities and levels in healthy participants.


- Determine the safety and tolerability of this drug in these participants.

OUTLINE: This is an open-label study.

Participants receive oral green tea extract (Polyphenon E) once daily for 4 weeks in the absence of unacceptable toxicity.

Participants are followed for 2 weeks.

PROJECTED ACCRUAL: A total of 44 participants will be accrued for this study.

Study Design

Masking: Open Label, Primary Purpose: Prevention


Unspecified Adult Solid Tumor, Protocol Specific


defined green tea catechin extract


Arizona Cancer Center at University of Arizona Health Sciences Center
United States




University of Arizona

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:54:04-0400

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