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Natalizumab in the Treatment of Rheumatoid Arthritis in Subjects Receiving Methotrexate

2014-08-27 03:54:20 | BioPortfolio

Summary

The purpose of this study is to determine the safety, tolerability and efficacy of natalizumab in subjects diagnosed with moderate to severe rheumatoid arthritis (RA) receiving concomitant treatment with methotrexate (MTX). It is thought that natalizumab may stop the movement of certain white blood cells, known as lymphocytes, into joint tissue. These cells are thought to cause damage in the joints leading to the symptoms of RA.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Rheumatoid Arthritis

Intervention

natalizumab, placebo

Location

University of Alabama at Birmingham
Birmingham
Alabama
United States
35294

Status

Terminated

Source

Elan Pharmaceuticals

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:54:20-0400

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Medical and Biotech [MESH] Definitions

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