Trial of a Novel Fibrinolytic (Alfimeprase) to Clear Thrombosed Vascular Access Devices

2014-08-27 03:54:45 | BioPortfolio


This trial is for patients with a central venous catheter (a vascular access device) that is not functioning properly (unable to withdraw blood). The trial compares a new blood clot dissolving agent (alfimeprase) against the currently used treatment.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment


Catheters, Indwelling




Cleveland Clinic Foundation
United States




ARCA Biopharma, Inc.

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:54:45-0400

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Medical and Biotech [MESH] Definitions

Catheters designed to be left within an organ or passage for an extended period of time.

Catheters inserted into various locations within the heart for diagnostic or therapeutic purposes.

Catheters inserted into the URINARY BLADDER or kidney for therapeutic or diagnostic purposes.

Catheters that are inserted into a large central vein such as a SUBCLAVIAN VEIN or FEMORAL VEIN.

A flexible, tubular device that is used to carry fluids into or from a blood vessel, hollow organ, or body cavity.

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Blood is a specialized bodily fluid that delivers necessary substances to the body's cells (in animals) – such as nutrients and oxygen – and transports waste products away from those same cells.  In vertebrates, it is composed of blo...

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