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An Open Label Study of a Peptide Vaccine in Patients With Stage III Colon Cancer

2014-08-27 03:55:28 | BioPortfolio

Summary

EP2101 is a new cancer vaccine containing 10 different peptide antigens. The vaccine is designed to activate the immune system to develop a response against tumor cells in order to delay or prevent the recurrence of cancer. This study will test the safety and measure the level of immune stimulating capability of EP2101 in patients with Colon Cancer.

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Colonic Neoplasms

Intervention

EP2101

Location

University of Southern California School of Medicine
Los Angeles
California
United States
90033

Status

Completed

Source

Epimmune

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:55:28-0400

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Medical and Biotech [MESH] Definitions

Tumors or cancer of the COLON.

Inflammation of the COLONIC DIVERTICULA, generally with abscess formation and subsequent perforation.

Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.

A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.

A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.

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