Study of Decision Making in Patients Participating in Phase I Clinical Trials

2014-08-27 03:55:29 | BioPortfolio


RATIONALE: Studying individuals who are enrolled in phase I clinical trials may help to improve the way in which clinical trials are conducted.

PURPOSE: This clinical trial is studying patients' personality traits, reasons for participating in the trial, and understanding of their medical situation, prognosis, and risks and benefits of participating in a phase I trial.



- Determine the range of personality traits of patients enrolled in a phase I clinical trial.

- Determine these patients' understanding of their medical situation and prognosis.

- Determine these patients' understanding of risks and benefits of phase I clinical trials.

- Determine these patients' reasons for participating in a phase I clinical trial.

- Determine the risk/benefit trade-offs of these patients.

- Determine the existential outlook of these patients.

- Determine the information gathering nature of these patients.

OUTLINE: This is a multicenter study.

Before beginning phase I clinical trial treatment, patients complete a survey over 30-45 minutes administered by an interviewer. Patients then self-administer the Temperament and Character Inventory assessment over 30 minutes.

PROJECTED ACCRUAL: Approximately 250 patients will be accrued for this study within 6 months.

Study Design

Masking: Open Label


Psychosocial Effects of Cancer and Its Treatment


psychosocial assessment and care


Robert H. Lurie Comprehensive Cancer Center at Northwestern University
United States




National Cancer Institute (NCI)

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:55:29-0400

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