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Electroconvulsive Therapy in Clozapine Refractory Schizophrenia

2014-08-27 03:55:54 | BioPortfolio

Summary

This study will evaluate electroconvulsive therapy (ECT) in patients who have not responded adequately to clozapine.

Description

ECT augmentation of clozapine will be compared to clozapine monotherapy in schizophrenic patients who continue to have psychotic symptoms despite optimal treatment with clozapine.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Masking: Open Label, Primary Purpose: Treatment

Conditions

Schizophrenia

Intervention

ECT, Clozaril

Location

Zucker Hillside Hospital
Glen Oaks
New York
United States
11004

Status

Active, not recruiting

Source

National Institute of Mental Health (NIMH)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:55:54-0400

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Medical and Biotech [MESH] Definitions

A chronic form of schizophrenia characterized primarily by the presence of persecutory or grandiose delusions, often associated with hallucination.

A type of schizophrenia characterized by abnormality of motor behavior which may involve particular forms of stupor, rigidity, excitement or inappropriate posture.

An obsolete concept, historically used for childhood mental disorders thought to be a form of schizophrenia.

A type of schizophrenia characterized by frequent incoherence; marked loosening of associations, or grossly disorganized behavior and flat or grossly inappropriate affect that does not meet the criteria for the catatonic type; associated features include extreme social withdrawal, grimacing, mannerisms, mirror gazing, inappropriate giggling, and other odd behavior. (Dorland, 27th ed)

An antipsychotic agent used in schizophrenia.

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