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Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma

2014-08-27 03:56:00 | BioPortfolio

Summary

The primary goal of this study is to determine if people with metastatic melanoma who receive Heat Shock Protein-Peptide Complex - 96 (HSPPC-96 or Oncophage) after surgery live longer than people who may or may not have surgery but who receive conventional chemotherapy including IL-2/DTIC. A second goal is to determine the safety and frequency of side effects in subjects who receive therapy with HSPPC-96.

Description

Primary Objective:

- To determine whether subjects with stage IV melanoma randomized to HSPPC-96 have longer survival than subjects randomized to physician's choice including interleukin-2 and/or dacarbazine/temozolomide and/or complete tumor resection.

Secondary Objective:

- To determine frequency of adverse events in subjects randomized to HSPPC-96.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Malignant Melanoma

Intervention

HSPPC-96 or Oncophage

Location

Birmingham
Alabama
United States

Status

Completed

Source

Agenus, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:56:00-0400

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Medical and Biotech [MESH] Definitions

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