Study Comparing the Safety and Efficacy of BMS-224818 to Cyclosporine, in Patients Receiving a Kidney Transplant, When Used in Combination With CellCept, Simulect, and Corticosteroids.

2014-08-27 03:56:11 | BioPortfolio


The purpose of this study is to see if BMS-224818 treatment will be as efficacious as cyclosporine at preventing acute rejection, and a superior safety / tolerability profile (better kidney function, better blood pressure, less lipid problems, less diabetes mellitus, etc.)

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention


Graft Rejection


LEA29Y, Belatacept


Univ. of Calif. - San Francisco
San Francisco
United States




Bristol-Myers Squibb

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:56:11-0400

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The immune responses of a host to a graft. A specific response is GRAFT REJECTION.

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An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.

Immunological rejection of leukemia cells following bone marrow transplantation.

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