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Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1

2014-07-23 21:55:07 | BioPortfolio

Summary

The purpose of this study is to evaluate modafinil, a cocaine treatment medication, and its interactions with intravenous (IV) cocaine.

Description

Placebo-controlled, escalating dose drug interaction study using a total of 12 cocaine users at a single site. Study duration will include four infusion sessions: 1) screening/baseline; 2) baseline; 3) 400mg/day steady-state modafinil; 4) 800 mg/day steady state modafinil. Infusion session will be 2 days in duration.

Study Design

Control: Dose Comparison, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Cocaine-Related Disorders

Intervention

Modafinil

Location

Medical University of South Carolina
Charleston
South Carolina
United States
29425 742

Status

Active, not recruiting

Source

National Institute on Drug Abuse (NIDA)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:55:07-0400

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Medical and Biotech [MESH] Definitions

Disorders related or resulting from use of cocaine.

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Disorders related to substance abuse, the side effects of a medication, toxin exposure, and ALCOHOL-RELATED DISORDERS.

Disorders related or resulting from abuse or mis-use of opioids.

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