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Kanglaite Injection Phase I Study

2014-08-27 03:56:20 | BioPortfolio

Summary

The Kanglaite Injection (KLT)is a novel broad spectrum anti-cancer injection produced from traditional Chinese medicinal herbs (the Coix Seed). It was approved in China in 1995 and has become the most popular anti-cancer drug in China. In June of 2001, the Phase I study of KLT commenced at the Huntsman Cancer Institute in Salt Lake City, Utah, with the objectives of 1) To determine the maximum tolerated dose (MTD) and the safety profile of KLT in patients with refractory solid tumors; 2) To determine the pharmacokinetics of KLT in patients with refractory solid tumors; and 3) To gather preliminary efficacy data. The method of testing is open-label, sequential cohort, dose-escalation study.

Study Design

Allocation: Non-Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Solid Tumors Refractory To Standard Therapy

Intervention

Kanglaite Injection (KLT)

Location

Huntsman Cancer Institue
Salt Lake City
Utah
United States
84112

Status

Completed

Source

KangLaiTe USA

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:56:20-0400

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