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Developmental Effects On Children Of Women Who Take Antiepileptic Drugs During Pregnancy

2014-07-23 21:55:44 | BioPortfolio

Summary

The purpose of this study is to determine if antiepileptic drugs (AEDs) differ in their neurodevelopmental effects. Specifically, do the children of the women with epilepsy differ in their behavioral and cognitive development depending on which AED their mother takes during pregnancy?

Description

This is a prospective investigation enrolling 285 to 380 women with epilepsy during the first two trimesters of their pregnancies. There are 25 clinical centers as well as the database center. The women will be taking one of the following AEDs: carbamazepine, phenytoin, valproate, or lamotrigine. Cognitive and behavioral testing of the child will be done up to the age of 6 years. The study does not change the woman's doctor and does not interfere with the care of the treating physician.

Study Design

Observational Model: Family-Based, Time Perspective: Prospective

Conditions

Epilepsy

Intervention

Differential Abilities Scale, Neuropsychological Testing

Location

University of Alabama
Birmingham
Alabama
United States
32294

Status

Active, not recruiting

Source

Emory University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:55:44-0400

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