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Treating Alcohol Use In Older Adults With Depression

2014-08-27 03:56:48 | BioPortfolio

Summary

The purpose of this study is to test the efficacy combining a treatment for depression with a treatment for alcohol dependence.

Description

This study aims to study 80 patients with comorbid alcohol dependence and a depressive syndrome. After appropriate detoxification, patients are started on either naltrexone 50 mg or placebo. After one week, sertraline is added in an open label fashion. It is hypothesized that those patients receiving combination therapy will last 3 months with follow-up tracking lasting 1 year.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Alcoholism

Intervention

NALTREXONE, Placebo

Location

University of Pennsylvania
Philadelphia
Pennsylvania
United States
19104

Status

Completed

Source

Department of Veterans Affairs

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:56:48-0400

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Medical and Biotech [MESH] Definitions

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An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.

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