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Beta Alethine in Treating Patients With Low-Grade Lymphoma

2014-08-27 03:57:15 | BioPortfolio

Summary

RATIONALE: Biological therapies such as beta alethine use different ways to stimulate the immune system and stop cancer cells from growing.

PURPOSE: Phase I/II trial to study the effectiveness of beta alethine in treating patients who have low-grade lymphoma.

Description

OBJECTIVES:

- Determine the antitumor effects of low-dose beta-alethine in patients with low grade B-cell lymphoma.

- Assess the effects of this regimen on delayed-type hypersensitivity in these patients.

- Assess the safety of this regimen in this patient population.

OUTLINE: This is an multicenter study.

Patients receive low-dose beta-alethine subcutaneously once every 2 weeks for a total of 6 doses in the absence of unacceptable toxicity. Patients with no evidence of tumor progression may receive additional courses of therapy.

Patients are followed for 2 weeks from the last dose or for a minimum of 30 days if they withdraw due to an adverse event.

PROJECTED ACCRUAL: Approximately 13-37 patients will be accrued for this study.

Study Design

Primary Purpose: Treatment

Conditions

Lymphoma

Intervention

beta alethine

Location

Victory Over Cancer
Rockville
Maryland
United States
20852

Status

Active, not recruiting

Source

National Cancer Institute (NCI)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:57:15-0400

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