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A Study of Thioctic Acid and Deprenyl in HIV-Infected Patients With Dementia

2014-08-27 03:59:17 | BioPortfolio

Summary

The purpose of this study is to see if it is safe and effective to give thioctic acid and deprenyl (selegiline hydrochloride), alone or in combination, to HIV-infected patients who have mild to moderate dementia (a decline in their mental abilities).

Description

Patients are randomized to receive thioctic acid alone, deprenyl alone, thioctic acid/deprenyl, or placebo alone for 10 weeks, after which all patients may receive active drug on an open-label basis. Patients must have seven clinic visits.

Study Design

Endpoint Classification: Safety Study, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Cognitive Disorders

Intervention

Thioctic acid, Selegiline hydrochloride

Location

Johns Hopkins Hosp
Baltimore
Maryland
United States
212876965

Status

Completed

Source

NIH AIDS Clinical Trials Information Service

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:59:17-0400

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