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Ondansetron Treatment for Alcoholism

2014-08-27 04:00:10 | BioPortfolio

Summary

The purpose of this study is to: a) evaluate the effectiveness of ondansetron (Zofran) in the treatment of alcohol dependent patients; b) investigate whether early versus late onset alcoholism predicts treatment outcome; and c) determine whether the early and late onset groups respond differently to treatment. Individuals will be "typed" into early onset and late onset alcoholism groups. Individuals will be randomly assigned to a 12-week outpatient treatment program.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Alcoholism

Intervention

ondansetron (Zofran)

Location

Substance Abuse Research Center, University of Texas Health Science Center
Houston
Texas
United States
77030

Status

Completed

Source

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T04:00:10-0400

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41st Annual Scientific Meeting of the Research Society on Alcoholism, June 16-20 - San Diego, California.

Medical and Biotech [MESH] Definitions

A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

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