Advertisement

Topics

Acute Otitis Media: Adjuvant Therapy to Improve Outcome

2014-07-23 22:00:26 | BioPortfolio

Summary

Acute otitis media is one of the most common diseases of childhood and is one of the major causes of hearing loss in children. Despite the availability of effective antibiotic therapy for otitis media, treatment failures, persistent effusions, and recurrences are common. This Phase III outpatient study aims to test whether adjuvant therapy (an antihistamine or a corticosteroid), in addition to antibiotic therapy, improves the acute and long-term outcomes of patients with acute otitis media. This study is targeted to recruiting 200 infants (age less than one year); patient (and parent) participation is estimated to continue for one year after enrollment.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Otitis Media

Intervention

Antihistamine, Corticosteroid

Location

Univ of Texas Med Branch Children's Hosp
Galveston
Texas
United States
77550

Status

Completed

Source

National Institute on Deafness and Other Communication Disorders (NIDCD)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T22:00:26-0400

Clinical Trials [418 Associated Clinical Trials listed on BioPortfolio]

Monteleukast Versus Inhaled Mometasone for Treatment of Otitis Media With Effusion in Children

Otitis media is one of the most common infections among children and is a complication in about 30% of common colds. The most common complication of acute otitis media is otitis media with...

Impact of Pneumococcal Conjugate Vaccines on Otitis Media and Acute Otitis Media in Swedish Children

The goal of this study is to look at the effect of pneumococcal conjugate vaccines (PCV) on physician-diagnosed otitis media (OM) and acute otitis media (AOM) incidence in Swedish children...

Xylitol Syrup for the Prevention of Acute Otitis Media in Otitis-prone Children

The primary objective of the proposed study is to determine the effectiveness and safety of orally administered viscous-adherent xylitol syrup given in a dose of five grams three times dai...

Acute Otitis Media and Nasopharyngeal Colonization Caused by Vaccine Serotypes of Strep Pneumoniae in Healthy Children

The purpose of this study is to assess the effectiveness of Prevnar 13 against pneumococcal acute otitis media.

Shared Decision Making in Parents of Children With Acute Otitis Media

This study will evaluate the efficacy of shared decision making in treatment of Acute Otitis Media in the Emergency Department setting.

PubMed Articles [1975 Associated PubMed Articles listed on BioPortfolio]

Antibiotic Recommendations for Acute Otitis Media and Acute Bacterial Sinusitis: Conundrum No More.

There has been a substantial change in the prevalence and microbiologic characteristics of cases of acute otitis media secondary to the widespread use of pneumococcal conjugate vaccines. Current trend...

Bacteriological Study of Otitis Media and Its Antibiotic Susceptibility Pattern.

Otitis Media is a prevailing and notorious infection in developing countries causing serious local damage and threating complication. Mainly in developing countries like Nepal, Otitis Media results be...

Risk of childhood otitis media with focus on potentially modifiable factors: A Danish follow-up cohort study.

Otitis media is the primary cause of antibiotic prescription in children. Two-thirds of all children experience at least one episode of otitis media before the age of 7 years. The aim of this study wa...

Microbiological Profile From Middle Ear And Nasopharynx In Patients Suffering From Chronic Active Mucosal Otitis Media.

Chronic otitis media is described as a tympanic membrane perforation and ear discharge for more than six weeks duration. Ascending infection from the nasopharynx into the middle ear cleft has been att...

Impact of influenza vaccine on childhood otitis media in Taiwan: A population-based study.

Acute otitis media (AOM) is a common infectious disease in children and usually accompanied by a preceding viral respiratory tract infection, especially in the preschool-age population. The study aime...

Medical and Biotech [MESH] Definitions

Inflammation of the ear, which may be marked by pain (EARACHE), fever, HEARING DISORDERS, and VERTIGO. Inflammation of the external ear is OTITIS EXTERNA; of the middle ear, OTITIS MEDIA; of the inner ear, LABYRINTHITIS.

Inflammation of the middle ear with purulent discharge.

Inflammation of the honeycomb-like MASTOID BONE in the skull just behind the ear. It is usually a complication of OTITIS MEDIA.

Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.

Inflammation of the middle ear with a clear pale yellow-colored transudate.

More From BioPortfolio on "Acute Otitis Media: Adjuvant Therapy to Improve Outcome"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

Pediatrics
Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...

Hearing
Hearing, auditory perception, or audition is the ability to perceive sound by detecting vibrations, changes in the pressure of the surrounding medium through time, through an organ such as the ear. Sound may be heard through solid, liquid, or gaseous mat...


Searches Linking to this Trial