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Selegiline in Outpatient Treatment for Cocaine Dependence - 1

2014-08-27 04:00:11 | BioPortfolio

Summary

The purpose of this study is to evaluate the efficacy and clinical safety of selegiline in the treatment of cocaine dependence and to assess neurotoxicity (Magnetic Resonance Imaging, MRI) post-hoc as a possible variable for future stratification in clinical trials.

Study Design

Control: Placebo Control, Masking: Double-Blind, Primary Purpose: Treatment

Conditions

Cocaine-Related Disorders

Intervention

Selegiline

Location

Friends Research Institute
Los Angeles
California
United States
90025

Status

Completed

Source

National Institute on Drug Abuse (NIDA)

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T04:00:11-0400

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Medical and Biotech [MESH] Definitions

Disorders related or resulting from use of cocaine.

These disorders are related to both SCHIZOPHRENIA SPECTRUM AND RELATED DISORDERS and DEPRESSIVE DISORDERS in terms of symptomatology, family history, and genetics. (DSM-V) .

The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking.

Disorders related to substance abuse, the side effects of a medication, toxin exposure, and ALCOHOL-RELATED DISORDERS.

SMOKING of COCAINE.

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